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REBEL Core Cast 108.0 – Angioedema

REBEL EM

Both conditions can range in severity from benign to life threatening (Wilkerson 2012). 2012; 14(11). Hereditary Angioedema (presents in childhood) and Acquired C1 Inhibitor Deficiency (adulthood) Both involve abnormalities in the level or function of the C1 inhibitor. J Allergy Clin Immune Tract 2017; 5(5): 1402-9. EBMedicine.net.

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SGEM386: Blood on Blood – Massive Transfusion Protocols in Older Trauma Patients

The Skeptics' Guide to EM

The transfusion tech calls to remind you that your protocol is currently under review, and asks if would you like the 1:1 or the 1:3 version of fresh-frozen plasma (FFP) to packed red blood cells (pRBC)? years ( 2 ). Falling is the most common cause of traumatic injury resulting in older adults presenting to the ED [4].

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Thrombotic Thrombocytopenic Purpura (TTP)

Core EM

Joly, 2017; Sawler, 2020) Fresh frozen plasma (FFP) (contains ADMTS-13) may be used to supplement ADAMTS-13 if there is a delay in initiating TPE in the emergency department (i.e. Scully, 2012) Citations: Balduini CL, et al. The first TPE session should be completed prior to administration of any biologic therapies. Ann Hematol.

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ToxCard: Iron

EMDocs

Coagulopathy: Parenteral vitamin K and/or fresh frozen plasma (FFP) as clinically indicated. Published 2012 Jul 1. 2012 Aug;39(8):719-24. Can titrate up to maximum of 40 mg/kg/hr, although hypotension may limit dose of deferoxamine. 10 Maximum daily dose of 6-8g total of defuroxamine. Arch Pediatr Adolesc Med. PMID: 15939855.

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