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Thrombotic Thrombocytopenic Purpura (TTP)

Core EM

Joly, 2017; Sawler, 2020) Fresh frozen plasma (FFP) (contains ADMTS-13) may be used to supplement ADAMTS-13 if there is a delay in initiating TPE in the emergency department (i.e. Scully, 2012) Citations: Balduini CL, et al. The first TPE session should be completed prior to administration of any biologic therapies.

Plasma 246
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REBEL Core Cast 108.0 – Angioedema

REBEL EM

Without the C1 inhibitor, the plasma-kallikrein-kinin system produces more bradykinin. Both conditions can range in severity from benign to life threatening (Wilkerson 2012). Fresh frozen plasma for progressive and refractory angiotensin-converting enzyme inhibitor-induced angioedema. 2012; 14(11). N Engl J Med.

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SGEM386: Blood on Blood – Massive Transfusion Protocols in Older Trauma Patients

The Skeptics' Guide to EM

The transfusion tech calls to remind you that your protocol is currently under review, and asks if would you like the 1:1 or the 1:3 version of fresh-frozen plasma (FFP) to packed red blood cells (pRBC)? years ( 2 ). Falling is the most common cause of traumatic injury resulting in older adults presenting to the ED [4].