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1,2 However, the European TTM1 trial in 2013 showed similar outcomes for those cooled to 33 degrees Celsius compared to 36 degrees Celsius, leading to a 2015 AHA class I recommendation of “cooling between 32 degrees Celsius-36 degrees Celsius.” 5,6 In 2021, the TTM2 trial was published. N Engl J Med. 2013;369(23):2197-206. N Engl J Med.
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