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Published 2013 Aug 15. 2022 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic LifeSupport; AdvancedLifeSupport; Pediatric LifeSupport; Neonatal LifeSupport; Education, Implementation, and Teams; and First Aid Task Forces.
A retrospective data review of the out-of-hospital cardiac arrest (OHCA) database from 2013-2015 demonstrated statistically significant differences in time from patient contact to administration of epinephrine between IV and IO groups (8.8 One study showed that average time to establish an IV in the prehospital setting was 4.4 minutes). [5]
1,2 However, the European TTM1 trial in 2013 showed similar outcomes for those cooled to 33 degrees Celsius compared to 36 degrees Celsius, leading to a 2015 AHA class I recommendation of “cooling between 32 degrees Celsius-36 degrees Celsius.” 5,6 In 2021, the TTM2 trial was published. N Engl J Med. 2013;369(23):2197-206. N Engl J Med.
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