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Transfusion Reactions

Core EM

Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%

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REBEL Core Cast 108.0 – Angioedema

REBEL EM

Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. Features Urticaria and pruritis Rapid onset (1-2 hours) IgE Dependent (Type I Hypersensitivity) Reactions An allergen cross-links two or more IgE molecules on mast cells or basophils and initiates a signal cascade leading to degranulation.

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Transfusion Reactions

Core EM

Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%

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STREAM-2: Half-Dose Tenecteplase vs Primary PCI in Older Patients with STEMI?

REBEL EM

The STREAM-1 trial found that for [2] patients with STEMI presenting within 3 hours of symptom onset and unable to attain PCI within 1 hour of first medical contact, a pharmaco-invasive strategy resulted in similar rates of death, shock, heart failure, or reinfarction compared to primary PCI. Paper: Van de Werf, F et al.

STEMI 138
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CT Angiography Head and Neck: Indications and Limitations

EMDocs

He also reports associated photophobia, nausea, and a single episode of vomiting in the lobby. He denies a history of similar headaches in the past. He denies any medical history, significant family history, or recreational drug use. Vital signs: Temperature 99.5F, HR 98 bpm, BP 162/86 mmHg, RR 14 per minute, oxygen saturation 99% on room air.

E-9-1-1 106
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Episode 162 Allergies Part 2: Shots, pills, & pens

This Podcast Will Kill You

FDA approves first medication to help reduce allergic reactions to multiple foods after accidental exposure. 2013): 966-973. Development of neffy, an Epinephrine Nasal Spray, for Severe Allergic Reactions. Have you ever wondered why we have so many different types of antihistamines? History Biology Arthur, Greer.