Pediatric EM Morsels

JULY 26, 2024

First line therapies for anti-NMBDA receptor encephalitis consists of… High dose steroids , IVIG, and PLEX – Therapeutic plasma exchange Only 50% of patient’s respond, and will require second line therapies such as Rituximab. Epub 2013 Dec 18. IV acyclovir for HSV coverage while awaiting PCR results. Lancet Neurol.

Plasma 271

Plasma OR ED Critical Care 271

Pediatric EM Morsels

AUGUST 9, 2024

Foles, 2024 ] In the US, from 2013-2018, cases increased from 362 to 1,306. 2013 Aug;20(4):337-9. Epub 2013 Feb 27. Worldwide, congenital syphilis complicates about 1 million pregnancies / year. Hussain, 2023 ] Leads to >300,000 perinatal deaths / year globally. Rates of congenital syphilis are increasing. Can identify T.

E-9-1-1 154

E-9-1-1 Plasma Emergency Department OR 154

REBEL EM

SEPTEMBER 13, 2023

Bradykinin Mediated Plasma globulins called kininogens release bradykinin and cause vascular permeability. Image: ( Morgan 2010 ) Features Absence of urticaria and pruritus Insidious onset (24-36 hours) ACE Inhibitors Inhibition of ACE hinders the degradation of bradykinin and can lead to idiosyncratic angioedema.

Frozen Plasma 105

Frozen Plasma Allergic Reaction FFP Plasma 105

Core EM

OCTOBER 16, 2024

2013 Feb;160(4):434-44. Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3% Hirayama F. Br J Haematol.

Allergic Reaction 188

Allergic Reaction Plasma ED Epinephrine 188

EMDocs

MAY 23, 2024

3 Measured in analytical testing : Laboratories measure plasma concentration using osmometers which measures values as a function of kilograms of solvent. Elsevier Mosby; 2013. Choice of the best equation for plasma osmolality calculation: Comparison of fourteen formulae. Osmolality and Osmolarity: Narrowing the Terminology Gap.

Plasma 93

Plasma EMS ED OR 93

EMDocs

JULY 11, 2023

A 2013 study found oral mucosal and head bleeding due to injury were most common in those < 6 months. The patient’s plasma is mixed with normal pooled plasma (NPP) which adds sufficient clotting factors to overcome the deficiency. Each unit of FVIII/kg raises the plasma FVIII level by 2%. 2013 Dec;163(6):1781-3.

Plasma 75

Plasma ALS OR Emergency Department 75

Core EM

OCTOBER 2, 2024

2013 Feb;160(4):434-44. Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3% Hirayama F. Br J Haematol.

Allergic Reaction 100

Allergic Reaction Plasma ED Epinephrine 100