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Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactionsAllergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%
Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactionsAllergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%
The overall incidence of biphasic reactions is unknown with rates quoted from < 0.5% up to 23% ( Lieberman 2005 , Rohacek 2014 , Tole 2007 , Grunau 2014 ). This varied incidence can be due to inconsistent definitions or inclusion of mild reactions. Which patients are at risk for experiencing biphasic reactions?
Hypersensitivity reaction to a GLP-1 agonist, type 1 diabetes mellitus, and pregnancy. Hypersensitivity/dermatologic: GLP-1 agonists are synthetic peptides; may lead to antibody formation and allergicreaction/injection site reaction. Reactions are usually minor: transient warmth, pruritis at injection site that resolves.
10 This procedure has well-described rare complications including infection, blood loss, allergicreaction, arrhythmia, pneumothorax if approaching via the internal jugular vein, embolization of the device, and pulmonary artery perforation or dissection. Optivol TM , measures thoracic impedance through an ICD or CRT-D device.
He also reports associated photophobia, nausea, and a single episode of vomiting in the lobby. He denies a history of similar headaches in the past. He denies any medical history, significant family history, or recreational drug use. Vital signs: Temperature 99.5F, HR 98 bpm, BP 162/86 mmHg, RR 14 per minute, oxygen saturation 99% on room air.
” History of Allergy 100 (2014): 214-226. “111 years of allergen-immunotherapy: a long and successful history of the only available disease-modifier in allergic diseases.” FDA approves first medication to help reduce allergicreactions to multiple foods after accidental exposure. 2015): 350-351.
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