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ACMT Toxicology Visual Pearl: Needle to Necrosis

ALiEM

Naloxone will not reverse the effects of xylazine; however, it is routinely given in unresponsive or obtunded patients presenting with an opioid toxidrome. In patients with minimal response to naloxone, xylazine toxicity may be suspected [10]. Published 2014 Mar 26. Forensic Sci Int. 2014;240:1-8. 2022;14(8):e28160.

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Xylazine: “Zombie Drug” is an Emerging Threat

ACEP Now

CASE A 30-year-old woman presents to the emergency department with left arm pain from a chronic wound. While naloxone can treat fentanyl overdose, overdose symptoms may persist when xylazine is involved. Opioid overdoses involving xylazine in emergency department patients: a multicenter study. Alexander RS, et al.

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emDOCs Revamp – Acute Chest Syndrome

EMDocs

mg q20-30 min per dose) PRN naloxone in case of respiratory depression Some patients have SCD crises pain plan for reference Antimicrobials 11 Ceftriaxone + azithromycin if penicillin allergy for both children and adults. 2014 Feb;69(2):144-51. C or 100.4 mg/kg, max 4 mg per dose q20-30min) or hydromorphone (0.01-0.02 mg/kg, max 0.4

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Sickle Cell Disease Module

Don't Forget the Bubbles

Naloxone (opioid antidote) should be available in ED in case of severe respiratory depression. A 6-year-old girl from Saudi Arabia was referred by her General Practitioner to the local emergency department. 2014; 349–356. In addition to opiates, continue to offer paracetamol and NSAIDS (unless contraindicated).

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