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The PROPHY-VAP Trial: Ceftriaxone to Prevent VAP in Patients with Acute Brain Injury

REBEL EM

3, 4 It is the most common nosocomial infection in patients on mechanical ventilation, and one of the leading causes of nosocomial infection among all patients in the ICU. 1, 2 Its occurrence often portends worse outcomes in intubated patients, whose projected hospital course was already tenuous. 4, 8 Paper: Dahyot-Fizelier, C.,

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Transfusion Reactions

Core EM

Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3% mg IF requiring IM Epi >3x, switch to IV Epi, 0.05-0.1

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Clinical Conundrums: Should You Give the First Dose of Antibiotics IV Before Discharging Home on Oral Antibiotics?

REBEL EM

This finding persists when looking at a number of other infections including skin and soft tissue infections (SSTI) ( First10EM ), pyelonephritis ( Strohmeier 2014 ) and even bone and joint infections ( Li 2019 ). This feels intuitive as the IV route seems like it would be stronger, faster, and fix the patient better than the oral route.

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EM@3AM: Amniotic Fluid Embolism

EMDocs

A) Amniotic fluid embolism B) Eclampsia C) Placental abruption D) Pulmonary embolism Answer: A Amniotic fluid embolism (AFE) is a rare but potentially fatal complication of pregnancy. AFE should be considered in a patient who experiences cardiorespiratory collapse during labor or shortly thereafter.

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emDOCs Revamp: Alcohol Withdrawal

EMDocs

fold higher risk of NSTI than the control group 12 For those without comorbidities , AUD exhibited a 15.2-fold fold higher risk of NSTI than the control group 12 For those without comorbidities , AUD exhibited a 15.2-fold fold higher risk of NSTI than the control group 12 For those without comorbidities , AUD exhibited a 15.2-fold

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SGEM#199: Therapeutic Hypothermia – What is it Good For?

The Skeptics' Guide to EM

He is now stabilized, fosphenytoin is being infused, you are getting ready to ship him to the neuro-ICU and wonder if cooling him down would help. His oxygen saturation begins to drop and you decide to intubate and mechanically ventilate. Background: We have covered hypothermia a number of times on the SGEM. Reference: Legriel et al.

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SGEM#346: Sepsis – You Were Always on My Mind

The Skeptics' Guide to EM

This has included the three large RCTs published in 2014-15 comparing early goal-directed therapy (EGDT) to usual care. It is the leading cause of death in the intensive care unit (ICU) in the US and the most expensive diagnosis. mg/dl or 107 umol/L). So, you ask yourself, is this guy really septic and should we bypass those fluids?

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