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Transfusion Reactions

Core EM

Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3% In: Wolfson A, ed. Hirayama F.

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Transfusion Reactions

Core EM

Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3% In: Wolfson A, ed. Hirayama F.

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REBEL Core Cast 108.0 – Angioedema

REBEL EM

Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. Without the C1 inhibitor, the plasma-kallikrein-kinin system produces more bradykinin. Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. 2015; 372(5):418-25.

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ToxCard: Crotalid Envenomation Part 2 – CroFab vs. AnaVip: What’s the Difference?

EMDocs

However, in 2015 crotalidae equine immune F(ab’) 2 (ANAVIP®) was approved by the FDA for rattlesnake envenomations, and distribution of this antivenom began in 2018. Plasma half-life of the F(ab’) 2 antivenom is significantly longer at 5.5 5 Figure 1. Table 1: Comparison of F(ab) and F(ab’) 2 antivenoms.