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Podcast 185.0: Anticoagulation Reversal

Core EM

2015 Dec 22;132(25):2412-22. Comparison between Prothrombin Complex Concentrate (PCC) and Fresh Frozen Plasma (FFP) for the Urgent Reversal of Warfarin in Patients with Mechanical Heart Valves in a Tertiary Care Cardiac Center. 2015 Dec 17;373(25):2413-24. Epub 2015 Nov 11. Circulation. doi: 10.1161/CIRCULATIONAHA.115.019628.

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REBEL Core Cast 108.0 – Angioedema

REBEL EM

2015; 372(5):418-25. Read More EMCrit: Podcast 145 – Awake Intubation Lecture from SMACC ERCast: Angioedema References: Baş M et al. A randomized trial of icatibant in ACE-inhibitor-induced angioedema. N Engl J Med. PMID 25629740 Hassen GW et al. J Emerg Med 2013; 44 (4): 764-772.

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SGEM386: Blood on Blood – Massive Transfusion Protocols in Older Trauma Patients

The Skeptics' Guide to EM

The transfusion tech calls to remind you that your protocol is currently under review, and asks if would you like the 1:1 or the 1:3 version of fresh-frozen plasma (FFP) to packed red blood cells (pRBC)? Noting with some relief that at least he isn’t anticoagulated, you activate the hospital massive transfusion protocol. years ( 2 ).

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EM@3AM: Amniotic Fluid Embolism

EMDocs

2015 May;28(7):793-8. ” Am J Obstet Gynecol 201(5): 445 e441-413. link] Fong A, Chau CT, Pan D, Ogunyemi DA. Amniotic fluid embolism: antepartum, intrapartum and demographic factors. J Matern Fetal Neonatal Med. doi: 10.3109/14767058.2014.932766. Epub 2014 Jun 30. PMID: 24974876. Young BK, Florine Magdelijns P, Chervenak JL, Chan M.

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Penetrating chest trauma

Don't Forget the Bubbles

a) A balanced ratio of 1:1:1 (platelets: FFP: packed red cells) The PROPPR trial showed us that balanced ratios are important. b) A balanced ratio of 1: 1:2 (platelets: FFP: packed red cells) The PROPPR trial showed us that balanced ratios are important. 2015 Jul;115(1):76-83. Epub 2015 May 19. And blood comes out.

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emDOCs Podcast – Episode 102: Hypocalcemia in Trauma and the Diamond of Death

EMDocs

FFP and platelets also contain citrate. Blood products, including both packed red blood cells and whole blood, are stored with the anticoagulant citrate, with can bind Ca and lower ionized Ca levels. Packed red blood cells (pRBCs) are stored with 3 grams of citrate per unit, while whole blood is stored with 1.66 grams of citrate per unit.

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