Don't Forget the Bubbles

JUNE 30, 2023

This was a randomised controlled multisite study comparing resuscitation of trauma patients requiring massive transfusion using either 1:1::1 or 1:1:2 ratios of platelets to plasma to red blood cells. Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) Trial: design, rationale and implementation. 2015 Jul;115(1):76-83.

E-9-1-1 139

E-9-1-1 FFP Plasma Emergency Department 139

Core EM

OCTOBER 2, 2024

Philadelphia, PA: Wolters Kluwer; 2015:979-984. Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%

Allergic Reaction 100

Allergic Reaction Plasma ED Epinephrine 100

EMDocs

JUNE 12, 2024

Two randomized controlled trials by Moore et al found that prehospital plasma administration in trauma patients is associated with hypoCa (53% vs 36%). How does this impact the prehospital environment? Prehospital blood product transfusion increases risk of hypoCa. Anaesth Intensive Care. 2011;39(1):46-54. Li K, Xu Y. Int J Clin Exp Med.

ALS 89

ALS FFP Plasma Emergency Department 89

Don't Forget the Bubbles

NOVEMBER 15, 2023

Have a look to see how their osmolarity and tonicity across the cell membrane compare to plasma. Renal (= urine output) : anti-diuretic hormone (ADH) release from the posterior pituitary is stimulated by microchanges in plasma osmolarity. What loss mechanisms do we need to consider? A fluid shift, if you will. Lancet (London, England).

Plasma 80

Plasma ALS ICU Critical Care 80

EMDocs

JULY 13, 2024

Plasma cell endometritis is associated with Chlamydia trachomatis infection. 2015 Feb 2;2015(2):CD001067. Chorioamnionitis and endometritis. Infect Dis Clin North Am. 1997 Mar;11(1):203-22. doi: 10.1016/s0891-5520(05)70349-4. PMID: 9067792. Paukku M, Puolakkainen M, Paavonen T, Paavonen J. Am J Clin Pathol. 1999 Aug;112(2):211-5.

EMS 64

EMS E-9-1-1 Plasma OR 64

FOAMfrat

AUGUST 15, 2024

Moreover, LTOWB also allows us to administer platelets and plasma, in addition to red cells, to promote clotting and homeostasis. If you don't have access to LTOWB and are administering component therapies such as PRBCs or plasma, this is still incredible and I highly encourage it! Like I said, some blood is better than no blood!

Plasma 69

Plasma Ambulance ALS Emergency Department 69

EMDocs

JULY 19, 2023

However, in extreme cases with highly toxic levels, one could consider plasma exchange if no other suitable alternative exists. 2015, March 26). Chelation is generally indicated in cases where patients are experiencing symptoms of toxicity (even the vague, non-specific ones) or there are elevated concentrations of mercury in blood.

ACS 66

ACS Plasma OR ED 66

Don't Forget the Bubbles

JULY 5, 2023

SCD, therefore, is not only a mechanical disease but there are also many other cellular and plasma factors as well as endothelial interaction that generate chronic inflammation. Anemia ; 2015.DOI:10.1155/2015/791498. DOI:10.1155/2015/791498. Plast Reconstr Surg – Glob Open 2015; 3: 83–86. References Adewoyin AS.

E-9-1-1 126

E-9-1-1 ACS OR ICU 126

EMDocs

NOVEMBER 2, 2024

The development of an inflammatory process is largely due to the infiltration of lymphocytes and plasma cells which ultimately result in nerve damage (e.g., 2015 Dec;21(6 Neuroinfectious Disease):1714-28 Carlson JA, Dabiri G, Cribier B, Sell S. demyelination as in tabes dorsalis) and subsequent death [10]. Accessed July 19, 2024.

EMS 92

EMS E-9-1-1 Plasma ALS 92

EMDocs

AUGUST 31, 2023

However, in 2015 crotalidae equine immune F(ab’) 2 (ANAVIP®) was approved by the FDA for rattlesnake envenomations, and distribution of this antivenom began in 2018. Plasma half-life of the F(ab’) 2 antivenom is significantly longer at 5.5 5 Figure 1. Table 1: Comparison of F(ab) and F(ab’) 2 antivenoms.

Allergic Reaction 72

Allergic Reaction Plasma ALS EMS 72

EMDocs

JUNE 3, 2023

Institutional protocols should be utilized, keeping in mind that either whole blood or a 1:1:1 ratio of packed red blood cells, platelets, and fresh frozen plasma are optimal. link] Published June 23, 2015. Young and Burgess classification of pelvic ring fractures. Radiopaedia.org. Published November 8, 2022. Radiopaedia.org.

ED 54

ED Operating Room ALS Frozen Plasma 54

Don't Forget the Bubbles

AUGUST 2, 2023

Pro-inflammatory states may also play a role, as patients with CRPS have significantly higher levels of plasma cytokines and chemokines. Orthop Traumatol Surg Res 2015; 101: pp. Published 2015 Jul 29. We know that fractures are the precipitating event in about 5–14% of cases and surgical procedures in 10–15%. Audouin-Pajot C.,

MPD 98

MPD ALS Plasma OR 98

FOAMfrat

SEPTEMBER 19, 2024

Along with inducing coagulopathy, venom toxins may contribute to local and/or systemic hemorrhage and plasma extravasation by means of basement membrane degradation within the vasculature. Other venom toxins carry a fibrinogenolytic effect which hinders coagulation (anticoagulation). Wilderness & Environmental Medicine , vol.

Emergency Department 90

Emergency Department Epinephrine OR Plasma 90