Core EM

OCTOBER 2, 2024

2017 Jul 1;9(1):4-8. Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3% L., & Arora, S.

Allergic Reaction 100

Allergic Reaction Plasma ED Epinephrine 100

REBEL EM

SEPTEMBER 13, 2023

J Allergy Clin Immune Tract 2017; 5(5): 1402-9. PMID 20954277 Sinnert R et al. Randomized Trial of Icatibant for Angiotensin- Converting Enzyme InhibitoreInduced Upper Airway Angioedema (CAMEO Study). PMID: 28552382 Wilkerson RG. Angioedema in the Emergency Department: An Evidence Based Review. Emergency Medicine Practice. EBMedicine.net.

Frozen Plasma 105

Frozen Plasma Allergic Reaction FFP Plasma 105

EMDocs

APRIL 10, 2024

1,2] Consider using a physiological marker to help identify inadvertent vascular injection, such as epinephrine. [3] If epinephrine is used, small initial doses ( <1 ug/kg) are preferred. Epidemiology Most common cause: inadvertent intravascular injection. 5,8] In one review the incidence of LAST was estimated to be 2.7

E-9-1-1 93

E-9-1-1 Plasma Epinephrine Life Support 93

ACEP Now

JULY 7, 2023

2 Standard management for VT and VF involves the use of electrical defibrillation, high-quality chest compressions, and epinephrine. 5 More recent literature defines “refractory” as VT or VF that is persistent or recurrent despite three shocks from a defibrillator, three rounds of epinephrine, and use of an antiarrhythmic (i.e.,

Defibrillator 98

Defibrillator OR ALS Epinephrine 98

NAEMSP

JANUARY 5, 2023

1] The Adult Cardiac Arrest ACLS algorithm currently includes epinephrine and either amiodarone or lidocaine as recommended pharmacologic therapies. Time to epinephrine in out-of-hospital cardiac arrest: A retrospective analysis of intraosseous versus intravenous access. 2017 Feb;35(2):222-226. minutes versus 5.4 minutes). [5]

E-9-1-1 52

E-9-1-1 Advanced Life Support Epinephrine Life Support 52

REBEL EM

NOVEMBER 6, 2023

to 1mg/kg/hr) Information regarding the vasopressors used in the study is as follows: Norepinephrine equivalents = norepinephrine mcg/kg/min + (phenylephrine mcg/kg/min/10) + epinephrine mcg/kg/min + (vasopressin units/min x2.5) Epub 2017 May 24. Epub ahead of print. PMID: 37586951 Mehaffey JH, et al. Ann Thorac Surg. 2022 Aug 22.

ICU 72

ICU Epinephrine ALS OR 72

ECG & Echo Learning

OCTOBER 2, 2022

Epinephrine Shock (any) Cardiac arrest Bronchospasm Anaphylaxis Bradycardia (second-line alternative) Infusion : 0.01 Effects of dopamine, norepinephrine, and epinephrine on the splanchnic circulation in septic shock: which is best? N Engl J Med 2017. N Engl J Med 2017. N Engl J Med 2017; 377:419.

E-9-1-1 52

E-9-1-1 ALS Coronary Epinephrine 52

REBEL EM

MAY 29, 2023

What They Did: Single-center, parallel, double blind, randomized controlled trial performed in a medical-surgical ICU (Mexico) Both groups received: Adjunctive vasopressin initiated at a dose of 0.03 NaCl over 6hrs once daily x3 doses Placebo: 500mL of 0.9% 95% CI 15.4 NaCl over 6hrs once daily x3 doses Placebo: 500mL of 0.9% 95% CI 15.4

ICU 145

ICU ALS Epinephrine OR 145

REBEL EM

SEPTEMBER 26, 2022

A meta-analysis of fifteen RCTs comparing blood product transfusion rates of cardiothoracic and surgery patients found significantly lower transfusion rates of FFP in TEG/ROTEM guided group compared to traditional tests, with no difference in survival rates (Fahrendorff 2017). Published 2017 Apr 13. Article: Kumar M et al.

FFP 52

FFP E-9-1-1 ICU ALS 52

Dr. Smith's ECG Blog

JULY 21, 2024

Epinephrine infusion was begun. In this study — Procainamide was superior to Amiodarone for terminating monomorphic VT, as well as having fewer adverse effects than Amiodarone ( Ortiz et al — Eur Heart J 1;38 (17): 1329-1335, 2017 ). An Impella device was placed to maintain cardiac output and perfusion pressures.

Defibrillator 113

Defibrillator Coronary ALS STEMI 113

ACEP Now

NOVEMBER 14, 2023

Published April 3, 2017. Administer nebulized tranexamic acid Inhaled nebulized TXA has been shown in one small, randomized control trial (RCT) and one retrospective study to hasten resolution of non-massive hemoptysis. 13,14 The typical regimen is 500 mg three times daily. EMCrit blog website. Accessed October 11, 2023. Lopez JK, Lee HY.

E-9-1-1 52

E-9-1-1 ALS Emergency Department OR 52

REBEL EM

JANUARY 23, 2023

2017 Jun 1;95(11):717-724. A contraindication, known allergy, or suspected intolerability to the study medication. The effectiveness of IV cetirizine was determined to be statistically non-inferior. Available at: [link] (Accessed: December 13, 2023). Monroe EW, Jones HE. An updated review. Arch Dermatol. 1977;113:80-90. Schaefer P.

Allergic Reaction 52

Allergic Reaction ED E-9-1-1 Emergency Department 52

ECG & Echo Learning

JANUARY 18, 2023

positive chronotropic medication (epinephrine, vasopressin, and/or atropine) is indicated – temporary pacing is indicated in cases of failure to respond to positive chronotropic medication – urgent angiography is indicated if the patient has not received previous reperfusion therapy.

STEMI 40

STEMI Coronary OR Defibrillator 40

The Skeptics' Guide to EM

JUNE 24, 2017

[display_podcast] Date: June 20th, 2017 Reference: Bernard et al. display_podcast] Date: June 20th, 2017 Reference: Bernard et al. They continue CPR, get intravenous access, give a round of epinephrine and then wonder if they should start rapid cooling en-route to the hospital with some cold saline. Circulation 2016.

CPR 100

CPR Epinephrine ALS Paramedic 100

EMDocs

JANUARY 4, 2024

Other Norepinephrine or epinephrine are preferred vasopressors when needed. Eds (2017). Consider lidocaine for associated dysrhythmias. 8 Consider intravenous lipid emulsion (ILE) for cardiotoxicity not responsive to other treatments. 9-12 Do not use this prophylactically in bupropion overdoses. Clin Toxicol (Phila). 2014;52(9):969-72.

Overdose 66

Overdose E-9-1-1 ALS Emergency Department 66