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ACMT Toxicology Visual Pearl – Apricot Kernels: Eat or pass?

ALiEM

2017, July 10). The amount of hydrogen cyanide in each kernel varies and ranges from 540 to 2,000 mg/kg [2]. The lethal dose range reported for cyanide in humans is 0.56-1.5 Grinding or chewing the kernel increases toxicity [4]. Antidotal therapy includes hydroxocobalamin, sodium nitrite, and sodium thiosulfate. Accessed August 20, 2023.

OR 169
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Pseudoparalysis of Parrot

Pediatric EM Morsels

[Kocher 1996, Pereira 2017] It is a complication of congenital syphilis , causing local periostitis, intense pain , and subsequent decreased movement. Kocher 1996, Pereira 2017] Syphilis is on the rise in the US. CDC 2023] In 2021, there were over 2800 cases of congenital syphilis, tripled from 2017.

Plasma 269
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Gelastic Seizures: No Laughing Matter

Pediatric EM Morsels

Nicotera, 2024 ] Can have associated autonomic features also: [ Bacus, 2023; Striano, 2017 ] Flushing Pupillary dilation Tachycardia Altered respirations Rare seizure type ~1% of all epilepsies Likely under-reported Ages: Typically seen in children ages 4 to 10 years. Vitamin B6 Deficiency ). Can even become status gelasticus.

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The Modified Valsalva Maneuver: Practical Treatment or Pointless Trick?

REBEL EM

What they did: Prospective randomized controlled trial, unblinded, multicenter study Conducted from January 2017 to December 2022 Patients with confirmed PSVT were randomly assigned to receive MVM, IV Adenosine, or combined therapy. This absence of detail leaves the study open to bias.

OR 137
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Thrombotic Thrombocytopenic Purpura (TTP)

Core EM

Annual incidence of approximately 2-4 cases/million/year (Kappler, 2017), with 90% of cases occurring in adulthood. Joly, 2017) Risk factors include: Female, 2:1 female to male predominance (Terrell, 2010) Black race Obesity TTP is a life-threatening condition with mortality of 10-20% despite targeted therapies.

Plasma 246
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Congenital Pulmonary Airway Malformation (CPAM)

Pediatric EM Morsels

I know we already know this, but it especially true when you are talking about trying to obtain images on a wiggling fetus somewhere around the size of a banana. Leblanc C, Baron M, Desselas, E, Phan, MH, Rybak A, Thouvenin G, Lauby C, Irtan S. Congential pulmonary airway malformations: state-of-the-art review for pediatrician’s use. Eur J Pediatr.

E-9-1-1 281
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Bougie: First Pass or Rescue Device?

ACEP Now

2017 May;69(5):540]. A study in the February issue of Annals conducted a meta-analysis of 18 studies and concluded that bougie use was associated with increased first-attempt intubation success. Some important limitations of this analysis should be recognized. There was no analysis of operator experience or expertise. 2023;42(6):445-9.

OR 73