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ToxCard: Organic Mercury Poisoning

EMDocs

7 We are commonly taught that metals are not amenable to treatment with activated charcoal (AC).However, In short, there is not a whole lot of evidence to support this, but if patient has had a recent ingestion and is not altered, you can consider gastrointestinal decontamination with AC. 2020 Aug 15;417:213343. Epub 2020 May 7.

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ToxCard: Acute Organophosphate Toxicity

EMDocs

8 Plasma butyrylcholinesterase (“pseudocholinesterase”) activity Easier to assay and is more widely available Red cell acetylcholinesterase (“true cholinesterase”) activity More accurate and specific Management: Patients require immediate intervention if there is concern for acute organophosphate poisoning. link] Updated September 14, 2020.

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Profound ST depression in II, III, aVF

Dr. Smith's ECG Blog

I did not think it was due to ACS, but we ordered an ED ECG immediately: What do you think? But in this case the clinical scenario is not right for acute ACS with OMI, and there is very high voltage, and the patient is very young, (though beware of young patients , even 29 year olds!! There is profound "inferior" ST Depression.

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ToxCard: Chronic Organophosphate Toxicity

EMDocs

link] Updated September 14, 2020. Accessed December 14, 2020. doi:10.1080/10773525.2015.1123848 Povey AC, Rees HG, Thompson JP, Watkins G, Stocks SJ, Karalliedde L. Two assays available used to help confirm diagnosis, however, do not guide treatment Low levels of activity are consistent with organophosphate poisoning.

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ToxCard: Crotalid Envenomation Part 2 – CroFab vs. AnaVip: What’s the Difference?

EMDocs

Plasma half-life of the F(ab’) 2 antivenom is significantly longer at 5.5 link] Li Z, Krippendorff BF, Sharma S, Walz AC, Lavé T, Shah DK. Published online November 2020. This size difference may lead to differences in the pharmacokinetic profiles of the two antibodies. 5 Figure 1. link] Full prescribing information.