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Transfusion Reactions

Core EM

Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3% Br J Haematol. link] Kwon, S.

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Pediatric Balanitis and Balanoposthitis

Pediatric EM Morsels

Balanitis and Balanoposthitis – Basics Terminology [Assim 2022, Dynamedex 2024, Perkins 2024] Balanitis – Inflammation of the glans penis Posthitis – Inflammation of the foreskin (prepuce) Balanoposthitis – Inflammation of both (ouch!)

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Transfusion Reactions

Core EM

Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3% Br J Haematol. link] Kwon, S.

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ToxCard: Crotalid Envenomation Part 2 – CroFab vs. AnaVip: What’s the Difference?

EMDocs

Accessed May 7, 2022. Accessed May 7, 2022. Accessed May 7, 2022. Accessed May 7, 2022. StatPearls Publishing; 2022. Accessed May 17, 2022. Table 1: Comparison of F(ab) and F(ab’) 2 antivenoms. References: Ubani C, DeGelorm A, Sollee D. Poison Control: The F(ab2)ulous Expanded Indication of Anavip | FCEP.

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emDOCs Podcast – Episode 94: GLP-1 Agonist Complications

EMDocs

American Gastroenterological Association issued a practice guideline in November 2022 recommending that semaglutide 2.4 Retrospective study published in 2022 of 81,752 adverse events associated with GLP-1 agonist therapy found an increased risk of pancreatitis, particularly with liraglutide (ROR 32.67; 95% CI 29.44-36.25).

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The PALACE Trial: Direct Oral PCN Challenge in Patients with Low-Risk PCN Allergy?

REBEL EM

What They Did: Parallel, 2-arm, noninferiority, open-label, multicenter, international randomized clinical trial Occurred in 6 specialized centers (3 in North America – US & Canada and 3 Outside of North America – Australia) Trial took place from June 2021 to December 2022 Used PEN-FAST to risk stratify patients.

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CT Angiography Head and Neck: Indications and Limitations

EMDocs

An understanding of the risks involved including allergic reaction, radiation exposure, contrast extravasation, and contrast-associated nephropathy allows for a thorough risk-benefit analysis prior to ordering these studies. American Journal of Roentgenology 2022, 218 (3), 544-551. Emerg Radiol 2022, 29 (2), 291-298.

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