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Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactionsAllergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%
Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactionsAllergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%
Accessed May 7, 2022. Background Crotalidae ovine polyvalent immune F(ab) (CroFab®) is the most widely available crotalid antivenom in the United States and is approved for severe crotalid envenomation with severe or progressive localized symptoms, systemic toxicity, and signs of hematologic toxicity on labs.
American Gastroenterological Association issued a practice guideline in November 2022 recommending that semaglutide 2.4 Hypersensitivity reaction to a GLP-1 agonist, type 1 diabetes mellitus, and pregnancy. Reactions are usually minor: transient warmth, pruritis at injection site that resolves. How do they work?
What They Did: Parallel, 2-arm, noninferiority, open-label, multicenter, international randomized clinical trial Occurred in 6 specialized centers (3 in North America – US & Canada and 3 Outside of North America – Australia) Trial took place from June 2021 to December 2022 Used PEN-FAST to risk stratify patients. Paper: Copaescu AM et al.
Balanitis and Balanoposthitis – Basics Terminology [Assim 2022, Dynamedex 2024, Perkins 2024] Balanitis – Inflammation of the glans penis Posthitis – Inflammation of the foreskin (prepuce) Balanoposthitis – Inflammation of both (ouch!) It’s even more distressing when the skin problem affects the penis.
Well keep it short, while you keep that EM brain sharp. A previously healthy 23-year-old male with no medical or surgical history presents to the ED with generalized malaise and no energy, progressively getting worse over the last six weeks. 10^9/L) Moderate (0.50.9 10^9/L) Severe (< 0.5 10^9/L) Generalized leukopenia (i.e. Medications: 25.6%
He also reports associated photophobia, nausea, and a single episode of vomiting in the lobby. He denies a history of similar headaches in the past. He denies any medical history, significant family history, or recreational drug use. Vital signs: Temperature 99.5F, HR 98 bpm, BP 162/86 mmHg, RR 14 per minute, oxygen saturation 99% on room air.
“111 years of allergen-immunotherapy: a long and successful history of the only available disease-modifier in allergic diseases.” ” Allergologie select 6 (2022): 248. FDA approves first medication to help reduce allergicreactions to multiple foods after accidental exposure. 2015): 350-351. .
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