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Thrombotic Thrombocytopenic Purpura (TTP)

Core EM

source: “Thrombotic Thrombocytopenic Purpura (TTP)”, 2022 , National Heart, Lung, and Blood Institute. Joly, 2017; Sawler, 2020) Fresh frozen plasma (FFP) (contains ADMTS-13) may be used to supplement ADAMTS-13 if there is a delay in initiating TPE in the emergency department (i.e. Scully, 2012) Citations: Balduini CL, et al.

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SGEM386: Blood on Blood – Massive Transfusion Protocols in Older Trauma Patients

The Skeptics' Guide to EM

Date: December 16th, 2022 Reference: Hohle et al. AEM December 2022 Guest Skeptic: Dr. Kirsty Challen is a Consultant in Emergency Medicine at Lancashire Teaching Hospitals. Date: December 16th, 2022 Reference: Hohle et al. years ( 2 ).

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Penetrating chest trauma

Don't Forget the Bubbles

a) A balanced ratio of 1:1:1 (platelets: FFP: packed red cells) The PROPPR trial showed us that balanced ratios are important. b) A balanced ratio of 1: 1:2 (platelets: FFP: packed red cells) The PROPPR trial showed us that balanced ratios are important. 2022 Dec;57(12):986-993. Trials 23, 384 (2022). And blood comes out.

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Recognition and Treatment of Thrombotic Thrombocytopenic Purpura

ACEP Now

Therapeutic plasma exchange (TPE) with fresh frozen plasma (FFP) is the first-line treatment, by simultaneously supplying fresh ADAMTS13 and removing anti-ADAMTS13 autoantibodies. References Sukumar S, Lämmle B, et al. Kessler CS, Khan BA, et al. Li XM, Mo XY, et al. 2021;46:556-9 Long B, Bridwell RE, et al.

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A guide to major haemorrhage management in paediatrics

Don't Forget the Bubbles

Karageorgos S, Ren D, Ranaweera M, et al. Major haemorrhage protocols typically include a mixture of packed red blood cells (pRBCs), platelets, and fresh frozen plasma (FFP). Platelets and FFP replace lost platelets and coagulation factors, which help with clotting and also provide some volume expansion. Published 2022 May 4.

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Major Trauma – Injuries by Assault

Don't Forget the Bubbles

According to the latest figures (2022), there were approximately 6,000 recorded offences where a child was a victim of violence, including physical assault, sexual abuse, and homicide. Since 2022, NFS has become a specific crime in its own right, separate from assault. link] Institute For Addressing Strangulation. TXA in head injuries.

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ED care of refugee populations from sub-Saharan Africa

EMDocs

Background: Refugees on the Rise As of 2022, it was estimated that there were 35.3 57 Adapted from: Long B, MacDonald A, Liang SY, et al. Global Trends Report 2022. link] Rother B, Pierre G, Lombardo D, et al. link] Franco JR, Cecchi G, Priotto G, et al. 1 By the end of 2023, 117.3 of the global population.

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