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Questions: What are the symptoms of second-generation antipsychotic overdose? How is second-generation antipsychotic overdose diagnosed? What is the treatment for patients who have overdosed on second-generation antipsychotics? 4 The specific incidence of second-generation antipsychotic drug overdose is unknown, however, 4.7%
Reference Lin M, Phipps M, Chan TM, et al. Digital Impact Factor: A Quality Index for Educational Blogs and Podcasts in Emergency Medicine and Critical Care. Ann Emerg Med. 2023;82(1):55-65. doi: 10.1016/j.annemergmed.2023.02.011
Broselow-Luten System: Supportive Data Physician estimates of weight can underdose children by 49% or overdose by up to 116%. PAWPER [Wells 2013, Silvagni 2022] Takes into account body habitus. Zhu 2022] In Nepalese children, the Broselow correlated well at lower weights, but accuracy decreased at higher weights >18 kg. [K
Sometimes this can be used to our advantage, like when we need to give subcutaneous fluids to a dehydrated patient without an IV, or when we need to give SQ medications for things like Sulfonylurea overdose , Hereditary Angioedema , or DVTs. Shen 2013, Nickerson 2014, Scolaro 2016 ] Singh et al proposed an algorithm to guide treatment.
A 2022 CDC report showed an overall trend of increasing mental health-related ED visits for children and young people aged 0-17 from 2019 to 2022. Take Home Points CWEmergencyMedicine Download References Beaudry G, Drouin O, Gravel J, et al. Published 2022 Jun 13. link] Donofrio JJ, Santillanes G, McCammack BD, et al.
Current AHA guidelines do not recommend routine use of calcium in cardiac arrest (Panchal, et al., Calcium acts as a vasopressor and inotropic agent (Lindqwister, et al., risk ratio >1) was 4% for ROSC, 6% for 30 day survival, and 4% for survival with a favorable neurologic outcome at 30 days (Vallentin, et al.,
Paper: Vallentin MF et al. Resus 2022. References: Vallentin MF et al. Resus 2022. Additionally, there were non-statistically significant trends toward lower survival and lower survival with good neurologic outcomes in patients receiving calcium at 30 to 90 days.
There are many underlying causes, such as stroke, central nervous system depression (opioid overdose, etc.), Hopkins, Erin, et al. 2022, www.ncbi.nlm.nih.gov/books/NBK507807/. and muscular insufficiencies from conditions such as myasthenia gravis. National Library of Medicine , StatPearls Publishing, 8 Jan. Metabolic Acidosis.
There have been documented cases of overdose, and of note, there is no known antidote. Sodhi M, Rezaeianzadeh R, Kezouh A, et al. Ahmann AJ, Capehorn M, Charpentier G, et al. Poison centers see nearly 1,500% increase in calls related to injected weight-loss drugs as people accidentally overdose. Bansal AB, Al Khalili Y.
REBEL Cast Ep113 – Defibrillation Strategies for Refractory Ventricular Fibrillation Click here for Direct Download of the Podcast Paper: Cheskes S, et al. REFERENCES: Cheskes S, et al. 2022 Nov 6 PMID: 36342151 Cheskes S, et al. Defibrillation Strategies for Refractory Ventricular Fibrillation. N Engl J Med.
Recently, xylazine has gained attention in the media with increasing reports of xylazine-related overdose deaths in patients. When combined with illicit opioids such as heroin and fentanyl, xylazine may increase the risk of fatal overdose given the augmented sedation and respiratory depression effects [2]. Published 2022 Aug 19.
Date: August 23rd, 2022 Reference: Schoenfeld et al. AEM August 2022 Guest Skeptic: Dr. Chris Bond is an emergency medicine physician and assistant Professor at the University of Calgary. Date: August 23rd, 2022 Reference: Schoenfeld et al. Reference: Schoenfeld et al.
Right as you’re making your bunk you get dispatched for a reported overdose with police enroute, no further information. We go into it with preconceptions of what to expect: “It’s a simple heroin overdose, we’ll wake them up and they’ll refuse, then we’ll go back to bed”. Iolascon A, Andolfo I, Russo R, et al. 21, 2022, p.
Questions: What are the clinical manifestations of bupropion overdose? How is bupropion overdose treated? How long should a patient be observed after a bupropion overdose? 1 In addition to intentional overdoses, there are multiple case studies of abuse (ingestion, insufflation, injection). hours, SR 3 hours, XL 5 hours.
Xylazine is a veterinary sedative that has been increasingly implicated in overdose deaths throughout the United States. percent of all overdose deaths in 2020. 1 Known by street names such as “tranq,” “tranq-dope,” or “zombie drug,” xylazine is increasingly found in patients with opioid overdose. References Friedman J, et al.
What are the treatment options for a benzonatate overdose? 7) Overdose literature review timeline: In 1986, the first two benzonatate fatalities were reported in the literature: a choking infant and an intentional overdose in a teenager. (8) There is no specific toxidrome or antidote for a benzonatate overdose.
According to the 2022 Annual Report of the National Poison Data System from America’s Poison Center, CCBs and BBs account for the sixth and seventh largest number of fatalities from overdose. References Gummin DD, Mowry JB, Beuhler MC, et al. 1 Recall that cardiac output is a function of both stroke volume and heart rate.
Elimination half-life data is not well established but increases in larger overdoses and as renal injury begins to occur. Metabolism of DEG adapted from Bessenhofer, et al. References: Abubukar et al. Nelson, et al. Accessed August 2022. FDA Consumer Magazine , June 1981, [link] Accessed August 2022.
In our case, the patient had accidentally overdosed on drugs prior to being found. Carsten L, et al. Accessed December 4, 2022 Swol, Justyna; Darocha, Tomasz; Paal, Peter; Brugger, Hermann; Podsiadło, Paweł; Kosiński, Sylweriusz; Puślecki, Mateusz; Ligowski, Marcin; Pasquier, Mathieu. Monika BM, Martin D, Balthasar E, et al.
Unfortunately, most cases are not so simple, with half of them being unintentional overdoses, many with a delayed presentation; some with delayed-release formulations, combined formulations, or co-ingestions, and some in patients with co-morbidities—all factors that make recognition and management more challenging. for death. for death.
Confounders to the GCS such as seizure and post-ictal phase, ingestions and drug overdose, as well as medications administered in the prehospital setting that impact GCS score should be documented. References Lulla A, et al. Accessed 2022, [link]. Spaite DW, Bobrow BJ, Keim SM, et al. Prehosp Emerg Care. J Safety Res.
In such cases — radiofrequency ablation of ectopic beats triggering malignant ventricular arrhythmias was needed for control of arrhythmic storm because the antiarrhythmic medications tried were ineffective ( Marrouche et al — JACC 5;43(9): 1715-20, 2004 ). The most common side effects of Quinidine is hypotension and QTc prolongation.
2022 Annual Report of the National Poison Data System®(NPDS) from America’s Poison Centers®: 40th Annual Report. LoVecchio, Frank, et al. CDC: May 14, 2024 Drug Overdose Death Rates. .” American Journal of Diseases of Children 137.9 1983): 870-873. Gummin, D.D., Mowry, J.B., Beuhler, M.C., Spyker, D.A., Rivers, L.J.,
2022 Annual Report of the National Poison Data System®(NPDS) from America’s Poison Centers®: 40th Annual Report. LoVecchio, Frank, et al. CDC: May 14, 2024 Drug Overdose Death Rates. .” American Journal of Diseases of Children 137.9 1983): 870-873. Gummin, D.D., Mowry, J.B., Beuhler, M.C., Spyker, D.A., Rivers, L.J.,
In a teen who presents with vomiting and abdominal pain, is this “just” viral gastroenteritis, or could this be a Tylenol overdose ? Cappelli M, Gray C, Zemek R, et al. Pediatrics June 2022; 149 (6): e2021053458. 2021-053458 Szucs LE, Pampati S, Li J, et al. Moral of the Morsel This is our lane. Pediatrics. 10.1542/peds.2021-053458
Date: December 26, 2024 Reference: Steinhauser S et al. In the United States alone, the burden is staggering: over six million individuals were estimated to have OUD in 2022. Emergency departments (EDs) are often the first point of contact for patients experiencing opioid-related crises, ranging from overdose to withdrawal.
He was admitted for a suspected kratom overdose and acute kratom withdrawal. In 2022, the National Poison Data system reported 1,278 cases involving kratom; about 45 percent of those cases required health care facility management. Gummin DD, Mowry JB, Beuhler MC, et al. Todd DA, Kellogg JJ, Wallace ED, et al. J Med Chem.
Background: Fentanyl has contributed to a significant increase in drug overdose deaths in recent years. A prospective study of 453 patients who were admitted after receiving naloxone reported life-threatening complications in over 1% of heroin-overdosed patients. Clinical Pearls: Naloxone is lifesaving in opioid overdoses.
We are in the midst of the worst overdose crisis in American history, with greater than 100,000 deaths in the last year on record. 1 Overdose is the leading cause of death among Americans 40-years-old and younger, accounting for more deaths than homicide, suicide, motor vehicle accidents, gun violence, and cancer.
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