article thumbnail

Tranq dope (fentanyl-xylazine combination): A new horizon in opioid withdrawal treatment

ALiEM

Alternatively, one can cut the 2 mg Suboxone (buprenorphine + naloxone combination) strips into 4 pieces after waiting for a longer washout period (72-96 hours of abstinence from non-medical opioids) before starting the induction. Drug Checking Quarterly Report (Q3 2022). 2022; 06/26/2023. 2022 May;14(5). 2011 Dec;6:1-4.

E-9-1-1 161
article thumbnail

ACMT Toxicology Visual Pearl: Needle to Necrosis

ALiEM

Naloxone will not reverse the effects of xylazine; however, it is routinely given in unresponsive or obtunded patients presenting with an opioid toxidrome. In patients with minimal response to naloxone, xylazine toxicity may be suspected [10]. Journal of Addiction Medicine 16(5):p 595-598, 9/10 2022. Published 2022 Aug 19.

Naloxone 169
professionals

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

SGEM#374: Bad Habits – Medications for Opioid Use Disorder in the Emergency Department

The Skeptics' Guide to EM

Date: August 23rd, 2022 Reference: Schoenfeld et al. AEM August 2022 Guest Skeptic: Dr. Chris Bond is an emergency medicine physician and assistant Professor at the University of Calgary. Date: August 23rd, 2022 Reference: Schoenfeld et al. He is successfully resuscitated using naloxone and is stable after an observation period.

article thumbnail

Overdose Deaths Decline Nationwide

Peter Canning

107,543 people died of drug overdoses in 2023 down from 111,029 in 2022. Harm reduction and the availability of naloxone. Ten years ago when I responded to an overdose, I was the only one carrying naloxone. This doesn’t include all those resuscitations where bystanders gave naloxone and 911 was never called.

article thumbnail

Overdose Decline Speculation

Peter Canning

Is the decline in drug overdose deaths more related to the increased availability of naloxone, improved treatment for people who use drugs, or changes in the street drug supply, which while still quite toxic may be less so due to adulteration with other chemicals? A recent article in NPR, The pipeline of deadly fentanyl into the U.S.

article thumbnail

Overdose in the Elderly Increasing

Peter Canning

mg of Naloxone X 2, and now the ETCO2 drops to 45, the SAT soon comes up to 99 and the patient opens her eyes and lifts her head, surprised to find herself surrounded by EMS and Fire. of all overdoses in 2020 to just 6% in 2022. in 2022, while those 24 and under decreased from 7.9% of all overdoses to 11.1%. per 100,000.

article thumbnail

Connecticut Overdose Deaths Decline for Second Year in a Row

Peter Canning

EMS has a pivotal role in helping to combat these deaths, both but providing resuscitation with naloxone, but also in helping steer those resuscitated patients toward treatment and harm reduction resources. In 2022, while xylazine’s presence went up, deaths with xylazine present went down.