EMDocs

APRIL 10, 2024

Metabolism of ester anesthetics is by plasma cholinesterase, whereas amides are metabolized by the cytochrome P450 system in the liver. [6] 6] Action of local anesthetics is dependent upon the molecule crossing the plasma membrane in a unionized form. [2] Poisoning & Drug Overdose. McGraw Hill; 2022. J Med Toxicol.

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E-9-1-1 Plasma Epinephrine EMS 93

EMDocs

SEPTEMBER 7, 2023

DEG is rapidly absorbed when ingested and can reach peak plasma and brain tissue concentrations within four hours of ingestion. Elimination half-life data is not well established but increases in larger overdoses and as renal injury begins to occur. Accessed August 2022. Accessed August 2022. McGraw Hill, 2019.

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E-9-1-1 ALS Emergency Department Plasma 66

ACEP Now

FEBRUARY 11, 2024

There have been documented cases of overdose, and of note, there is no known antidote. Poison centers see nearly 1,500% increase in calls related to injected weight-loss drugs as people accidentally overdose. Updated December 11, 2022. Diabetes Care. 2018;41:258–66. CNN website. Published December 18, 2023. 2006;47(12):2207.

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