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Episode 82 – When Normal Labs Aren’t Necessary

The Curious Clinicians

One well-known study bled volunteers to a hemoglobin of 5 g/dL, while keeping them isovolemic with albumin or plasma infusions. The subjects’ blood was less viscous than normal, due to the isovolemic replenishment with plasma and albumin, making it flow more easily. December 19th, 2023. hours), Non-Physician Attendance (0.5

Plasma 52
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Popular Antiobesity Medications Bring New Challenges to Emergency Physicians

ACEP Now

One side effect of this medication is that it can reduce the absorption of antiepileptic medications such as valproate, vigabatrin, and lamotrigine and reduce their plasma concentration, thus putting patients taking these medications at higher risk of seizure. Published December 18, 2023. ACS Chem Neurosci. Updated May 16, 2023.

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Profound ST depression in II, III, aVF

Dr. Smith's ECG Blog

I did not think it was due to ACS, but we ordered an ED ECG immediately: What do you think? But in this case the clinical scenario is not right for acute ACS with OMI, and there is very high voltage, and the patient is very young, (though beware of young patients , even 29 year olds!! There is profound "inferior" ST Depression.

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Penetrating chest trauma

Don't Forget the Bubbles

This was a randomised controlled multisite study comparing resuscitation of trauma patients requiring massive transfusion using either 1:1::1 or 1:1:2 ratios of platelets to plasma to red blood cells. This post is part of the PEM Adventure at NEPTUNE 2023, hosted by Dani, Kat, Costas and Sarah. to −0.5%]; P  = 0.03.). Brie-liiant!

E-9-1-1 139
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ToxCard: Crotalid Envenomation Part 2 – CroFab vs. AnaVip: What’s the Difference?

EMDocs

Plasma half-life of the F(ab’) 2 antivenom is significantly longer at 5.5 Accessed August 17, 2023. link] Li Z, Krippendorff BF, Sharma S, Walz AC, Lavé T, Shah DK. F(ab) is smaller, consisting of a single antigen binding site, while F(ab’) 2 consists of two antigen-binding sites linked together by an antibody “hinge” region.