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Tranq dope (fentanyl-xylazine combination): A new horizon in opioid withdrawal treatment

ALiEM

We have certainly seen patients who have pain which is controlled and still have psychomotor agitation and sympathetic activation, leading some to require ICU admission for dexmedetomidine and/or ketamine infusion. 2024 study [16]. DOI: Papudesi BN, Malayala SV, Regina AC. 2024 Oct 8:S0735-6757(24)00523-0. 2023 [book].

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First10EM Journal Club: January 2025

Broome Docs

2024 Nov 22;17(1):177. 2024 Nov 18:e245981. 2024 Oct 26;404(10463):1645-1656. 2024 Jun;23(6):577-587. Epub 2024 Apr 20. 2024 Oct 9. Garcia SI, Jacobson A, Moore GP, Frank J, Gifford W, Johnson S, Lazaro-Paulina D, Mullan A, Finch AS. Airway, breathing, cellphone: a new vital sign? Int J Emerg Med.

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A fascinating electrophysiology case. What is this wide complex tachycardia, and how best to manage it?

Dr. Smith's ECG Blog

Ischemia from ACS causing the chest discomfort, with VT another consequence (or coincidence)? Cardioversion will address the rhythm problem immediately, also if the chest discomfort subsides when SR is restored, ischemia from ACS becomes much less likely. In either case, prompt cardioversion is indicated.

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Another deadly triage ECG missed, and the waiting patient leaves before being seen. What is this nearly pathognomonic ECG?

Dr. Smith's ECG Blog

The patient was upgraded to the ICU for closer monitoring. Accessed May 28, 2024. showed that , when T-waves are inverted in precordial leads, if they are also inverted in lead III and V1, then pulmonary embolism is far more likely than ACS. looked at consecutive patients with PE, ACS, or neither. Kosuge et al.

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Diagnostic Errors, Revisited: Where Do We Go Wrong, and How Can We Change?

ACEP Now

After developing encephalopathy and hypoxemic respiratory failure, the patient was transferred to the ICU. Further diagnostic testing in the ICU identified salicylate toxicity. Available from: [link] Newman-Toker DE, Nassery N, Schaffer AC, et al. Published 2024 Jan 19. Comparative Effectiveness Review, No. BMJ Qual Saf.

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Rethinking Fluid Resuscitation in Vaso-Occlusive Crisis: Is Lactated Ringer’s the Superior Choice?

REBEL EM

Both these physiologic principles and recent preclinical evidence have called into question whether NS is the best resuscitation fluid for patients experiencing VOE due to concerns its tonicity and tendency to induce acidosis may promote sickling ( Carden 2017a , Carden 2017b , Alwang 2024 ). Microcirculation. 2017;24(5):10.1111/micc.12353.

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105 – The Grapes of Pseudomonas’ Wrath

The Curious Clinicians

It’s easy to think of bacteria as always “wanting” to infect a host as quickly and aggressively as possible (and if you’ve ever taken care of someone with an acute PA bloodstream infection, you know how fast they can go from healthy to needing the ICU). Episodes prior to January 1, 2024, will remain free.

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