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Clinical impact: Rather than arguing with the patient about the likelihood of this phenomenon occurring and whether this is a true allergy, the patient is informed that they do not need to immediately start treatment to receive care in the hospital. Multimodal medication options for fentanyl-xylazine withdrawal management in London et al.
A thorough review of vital signs, physical exam findings and a complete blood count with differential, renal function panel and urinalysis offer valuable information in the patient being worked up for HUS. This of course, is made easier if you can get a stool sample to analyze in the first place. Schnadower, D., Finkelstein, Y.,Desai,
If this EKG were handed to you to screen from triage without any clinical information, what would you think? In fact, Kosuge et al. Stein et al. This is a paper worth reading : Marchik et al. Kosuge et al. Witting et al. looked at consecutive patients with PE, ACS, or neither. What do you think?
Article: Vaeli Zadeh A, Wong A, Crawford AC, Collado E, Larned JM. It’s not mentioned whether the authors attempted to identify additional studies by checking the references of the selected articles or by contacting the original paper authors for more information. times more intubations and 2.15
An expert committee appraised the evidence behind recommendations to avoid imaging to inform the 2022 NICE guidance. Discussion may be supported by patient information materials, particularly the provision of information in multiple languages. 2019-0134 Hirtz D, Ashwal S, Berg A, et al. J Trop Pediatr. 2020;66(3):299-314.
Angiogram No obstructive epicardial coronary artery disease Cannot exclude non-ACS causes of troponin elevation including coronary vasospasm, stress cardiomyopathy, microvascular disease, etc. Lindahl et al. Optical coherence tomography, due to its high resolution, may provide additional information [ 10,13 ]. From Gue at al.
Learning points: Both patients and other medical providers can report confusing and often contradictory information that obfuscates the diagnosis (in this case, WPW). Although recognition of OMI was not affected by administration of morphine in this case, use caution with analgesia in ongoing ACS without a definitive plan for angiography.
He sent it to me with no other information and I wrote back "100% diagnostic of LBBB with inferior-posterior-lateral OMI" There is atrial paced rhythm with Left Bundle Branch Block (LBBB). The cath report showed: Significant stenosis with subtotal occlusion (99%) in the prox to mid Lcx, culprit of ACS, TIMI flow 1. 2021;23:187.
2020.09.082 Full prescribing information. link] Full prescribing information. link] Li Z, Krippendorff BF, Sharma S, Walz AC, Lavé T, Shah DK. Unified Treatment Algorithm for the management of crotalid snakebite in the United States: results of an evidence-informed consensus workshop. Bush SP, Ruha AM, Seifert SA, et al.
Antonaci L, et al. Tritos NA, et al. Levi M, et al. Fishbein MH, et al. Cetinkaya PG, et al. Niu T, et al. Verkuijl SJ, et al. Varni JW, et al. Dias FC, et al. Peter C, et al. Ahlberg R, et al. Shir A, et al. Kuypers KLAM, et al. Hegeman EM, et al.
Hopefully in a few minutes you’ll at least have a few morsels more of information to stave off all the trainees who are undoubtedly much smarter than you on the ward round. Type 1 is the acute deterioration in kidney function seen in cardiogenic shock from ACS. Today we tackle a somewhat nebulous syndrome. – Mullens, W.,
An ECG was texted to me (Smith) without any clinical information: What did I say? This clinical information followed: "The patient had a COPD exacerbation with a prehospital SpO2 of 60%. This clinical information followed: "The patient had a COPD exacerbation with a prehospital SpO2 of 60%. Kosuge et al. Witting et al.
There were zero patients in this study with a "normal" ECG who had any kind of ACS! Deutch et al. This defies all previous data on acute MI which would show that even undetectable troponins do not have a 100% negative predictive value. So this study is actually worthless. West J Emerg Med 2024).
The NIHSS cutoff that predicts outcomes is 4 points higher in AC compared with PC infarctions. While MRI is more resource and time intensive, studies have shown that a 6-minute protocol can give sufficient information to dictate treatment in the right setting. References: Gaillard F, Glick Y, Tatco V, et al. Arch Neurol.
Smith: If this is ACS (a big if), t his is just the time when one should NOT use "upstream" dual anti-platelet therapy ("upstream" means in the ED before angiography). History sounds concerning for ACS (could be critical stenosis, triple vessel), but differential also includes dissection, GI bleed, etc. Knotts et al.
MOREVER, the morphology of the TWI is just not right for ACS. S1Q3T3 This is a paper worth reading : Marchik et al. Kosuge et al. showed that, when T-waves are inverted in precordial leads, if they are also inverted in lead III and V1, then pulmonary embolism is far more likely than ACS. inverted T-waves in V1 and V2, 1.8;
link] Shvilkin et al. link] Shvilkin et al. Thus, the very well informed physician could differentiate these ECGs from those of an LBBB patient with MI: 1) no concordance 2) no excessive discordance 3) LBBB with tachycardia, probably rate related 4) subsequent T wave inversion that, according to Shvilkin et al.,
Taking a different approach than the authors of the AHRQ report, Auerbach et al used a “look back” approach to perform both qualitative and quantitative evaluations of the types and frequencies of errors occurring in hospital settings. References Newman-Toker DE, Peterson SM, Badihian S, et al. Auerbach AD, Lee TM, Hubbard CC, et al.
The fire department, who operate at an EMT level in this municipality, arrived before us and administered 324 mg of baby aspirin to the patient due to concern for ACS. Reference on Troponins: Xenogiannis I, Vemmou E, Nikolakopoulos I, et al. Lindahl et al. From Gue at al.
Background Information: Atrial fibrillation with rapid ventricular rate (RVR) is one of the many tachydysrhythmias we encounter in the Emergency Department (ED). Paper: Mason JM, et al. These results were corroborated with other another study by Gritensko et al. Sepsis, hyperthyroidism, dehydration, heart failure, ACS, etc).
Background Information: Multiple illness severity scores have been developed for use after out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA). Unfortunately, these rely on information that is not immediately available to providers in the early hours following return of spontaneous circulation (ROSC).
He had no symptoms of ACS. greater than 40mS, V1-V2" Meyers interpretation: I was sent this ECG with no clinical information whatsoever, and I responded: "Easily diagnostic of acute LAD occlusion." His HEAR score (before troponin resulted) was documented at 3, with documentation stating "low suspicion for ACS." See text ).
Sodhi M, Rezaeianzadeh R, Kezouh A, et al. Ahmann AJ, Capehorn M, Charpentier G, et al. Contrave (naltrexone HCl/bupropion HCl) prescribing information. ACS chemical neuroscience molecule spotlight on Contrave. ACS Chem Neurosci. Bansal AB, Al Khalili Y. JAMA Health Forum. 2023;4(4):e230493. Steatorrhea.
Written by Pendell Meyers I was reading ECGs in a database (without any clinical information) when I came to this one: What do you think? You must understand this and the dynamic nature of ACS to provide excellent care for such patients. Seeing only this ECG with no context, I thought this ECG was within normal limits.
The ECG is diagnostic for acute transmural infarction of the anterior and lateral walls, with LAD OMI being the most likely cause (which has various potential etiologies for the actual cause of the acute coronary artery occlusion, the most common of which is of course type 1 ACS, plaque rupture with thrombotic occlusion).
Evaluate and treat seizures or SE after CA in the context of other available clinical information because other systemic factors may influence the occurrence of seizures or SE and the effectiveness of treatment (90%, 18/20). Reference: Hirsch KG, Abella BS, Amorim E, et al; American Heart Association, Neurocritical Care Society.
I sent this "normal" ECG without any information to a number of ECG enthusiasts, who were all concerned about possible OMI - whether subtle high lateral OMI with inferior reciprocal change, or subtle inferior OMI with high lateral reciprocal change. Take home 1. C ircumflex occlusions can have subtle to no ECG changes 3.
3–8 Shi et al. When the ECG is nondiagnostic for coronary occlusion, or the patient is suspected of having a non-occlusion MI, consider echocardiography to inform the decision for angiography. Sandoval Y, Smith SW, Sexter A, et al. Shi S, Qin M, Shen B, et al. Guo T, Fan Y, Chen M, et al. of Cardiology AC, Others.
Meyers : This ECG was texted to me with no clinical information, and my response was: "That looks like a very subtle LAD OMI. CLICK HERE — for a brief article by Rowlands et al that explains these concepts in more detail. Very very subtle one. What happened?"
I sent this to Dr. Meyers without any other information, and he responded, “do you have a prior to make sure that it is all just because of the delta wave? The emergency physician wasn’t sure what to make of the changes from one ECG to the next but was concerned about ACS. Rosner et al. What do you think? What do you think?
However, this additional information was supportive. Patients like her are the reason we are advocating for a change in the ACS paradigm from STEMI to OMI. Armstrong et al attempted to study it but may have included too many 'obvious' cases - the criteria from that paper would certainly have missed this case.
Here is a video lecture of subtle LAD occlusion: One hour lecture on Subtle ECG Findings of Coronary Occlusion The 3-variable formula comes from this paper: Smith SW et al. The 4-variable formula is based on this paper: Driver, BE et al. Case 3 I was reading a stack of ECGs yesterday, and saw this one, with no clinical information.
When I saw this without any other information, I said it was very suspicious for a high lateral MI. The clinicians later stated they had had no suspicion of ACS, but that the faculty wanted a troponin anyway. Sandoval Y et al. He had a triage ECG at time 0 (ECG-1): Computer read, with Physician overread: Sinus rhythm.
I assumed it was from a patient with symptoms compatible with ACS/OMI. If you are convinced by all the data, including the troponin, that the patient's pain is due to ACS, and he has persistent pain, then he should go to the cath lab. Wereski R, Chapman AR, Lee KK, Smith SW, Lowe DJ, Gray A, et al. What do you think?
I sent the ECG to Dr. Meyers without any information, and he immediately replied, “inferior OMI.” As recurrent ischaemia is the principle event reduced by early intervention in NSTE-ACS, these are important endpoint events occurring with delayed angiography and there is a consistent signal for harm now from two data sources.”[5]
Supplementing information from VBGs Unlike pH, PCO 2 , and HCO 3 , there are no correlations or conversions that reliably determine oxygenation status from a VBG (1, 10). References/Further Reading (1) Byrne AL, Bennett M, Chatterji R, Symons R, Pace NL, Thomas PS. 11) Webb RK, Ralston AC, Runciman WB. PMID: 11685301. (10)
32 Relying on easily and rapidly obtained information, these simple and low-cost tools may be particularly useful in low resource settings and in cases where time or severity of patient presentation does not permit additional workup. Fournier gangrene: an histori9]al reappraisal. Sugihara T, Yasunaga H, Horiguchi H, et al.
Also consider non-hemorrhagic volume depletion, dehydration : orthostatic vitals may uncover this [see Mendu et al. (3)]. Annotated Bibliography For an excellent overview of ED Syncope management , see this article by Kessler C et al. Del Rosso A, et al. Other studies 1) EGSYS score (full text link). Heart 2008;94(12):1620–6.
Use of CFTR modulators in pregnancy: new information for neonatal, paediatrics and midwifery teams. Pecenka C, et al. Winkler AE, et al. Bonifacio SL, et al. Brosnan B, et al. Panda PK, et al. Tangwijitsakul H, et al. Gunnarsdottir K, et al. Chong KH, et al. Blaabæk EH, et al.
Opioids do not cause ACS but they can exacerbate hypoxia in patients with ACS. Older children and adults usually present with ACS 2-3 days after hospitalisation due to pulmonary infarction (in situ sickling), hypoventilation due to rib infarction (which may be exacerbated by recent narcotic administration) or fat embolism.
To assess the clinical impact and relevance of these concerns, Alwang et al. Paper: Alwang AK, Law AC, Klings ES, Cohen RT, Bosch NA. PMID: 28423290 Kidwell K, Albo C, Pope M, et al. PMID: 24066745 Self WH, Semler MW, Wanderer JP, et al. PMID: 29485926 Semler MW, Self WH, Wanderer JP, et al. JAMA Intern Med.
Although technology like electronic health records (EHRs) were initially introduced as tools for improving team communication and streamlining information sharing, they have instead often isolated ED teams, siloing clinicians, who are hunched over keyboards rather than communicating at the bedside. References Edmondson AC.
I suspect pulmonary edema, but we are not given information on presence of B-lines on bedside ultrasound, or CXR findings. This presentation clearly indicates more than simple ACS ( A cute C oronary S yndrome ). Or I suspect that there is OMI simultaneous with another pathology. We certainly know that there is hypoxia.
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