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This 29 year old African American patient was found down, unconscious, not breathing and was given 2 mg of intranasal naloxone by a bystander. I did not think it was due to ACS, but we ordered an ED ECG immediately: What do you think? He then received bag-valve-mask ventilations for several minutes until he became responsive.
SCD, therefore, is not only a mechanical disease but there are also many other cellular and plasma factors as well as endothelial interaction that generate chronic inflammation. Opioids do not cause ACS but they can exacerbate hypoxia in patients with ACS. Morphine sulphate is the commonest strong opioid to start with.
A 33-year-old male with a history of drug use presented to the emergency department (ED) for extreme agitation after receiving two doses of 2 mg naloxone by EMS for respiratory depression. Kruegel AC, Gassaway MM, Kapoor A, et al. Gold MS, Pottash AC. That is, they experienced nausea, vomiting, chills, myalgias, and diarrhea.
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