Dr. Smith's ECG Blog

FEBRUARY 18, 2022

It was shown to me with worry for ischemic ST elevation, which is certainly possible from severe CO toxicity, or concomitant ACS. Intravascular Neutrophil Activation Due to Carbon Monoxide Poisoning What do you think of this ECG?

ACS 52

ACS Plasma OR STEMI 52

ACEP Now

FEBRUARY 11, 2024

One side effect of this medication is that it can reduce the absorption of antiepileptic medications such as valproate, vigabatrin, and lamotrigine and reduce their plasma concentration, thus putting patients taking these medications at higher risk of seizure. ACS chemical neuroscience molecule spotlight on Contrave. ACS Chem Neurosci.

Overdose 52

Overdose ACS Plasma ALS 52

EMDocs

AUGUST 31, 2023

Plasma half-life of the F(ab’) 2 antivenom is significantly longer at 5.5 link] Li Z, Krippendorff BF, Sharma S, Walz AC, Lavé T, Shah DK. F(ab) is smaller, consisting of a single antigen binding site, while F(ab’) 2 consists of two antigen-binding sites linked together by an antibody “hinge” region. 5 Figure 1. 2016;8(1):113-119.

Allergic Reaction 94

Allergic Reaction Plasma ALS EMS 94

EMDocs

JUNE 7, 2023

8 Plasma butyrylcholinesterase (“pseudocholinesterase”) activity Easier to assay and is more widely available Red cell acetylcholinesterase (“true cholinesterase”) activity More accurate and specific Management: Patients require immediate intervention if there is concern for acute organophosphate poisoning. Toxicology. 2001;160(1-3):27-33.

E-9-1-1 98

E-9-1-1 ICU Emergency Department ED 98

EMDocs

JUNE 14, 2023

doi:10.1080/10773525.2015.1123848 Povey AC, Rees HG, Thompson JP, Watkins G, Stocks SJ, Karalliedde L. Two assays available used to help confirm diagnosis, however, do not guide treatment Low levels of activity are consistent with organophosphate poisoning. 3 However, may be helpful in diagnosing the chronic toxicity forms. 2016;22(1):68-79.

E-9-1-1 92

E-9-1-1 Emergency Department Plasma ACS 92

EMDocs

JULY 19, 2023

7 We are commonly taught that metals are not amenable to treatment with activated charcoal (AC).However, In short, there is not a whole lot of evidence to support this, but if patient has had a recent ingestion and is not altered, you can consider gastrointestinal decontamination with AC.

ACS 87

ACS Plasma OR ED 87

Don't Forget the Bubbles

JULY 5, 2023

SCD, therefore, is not only a mechanical disease but there are also many other cellular and plasma factors as well as endothelial interaction that generate chronic inflammation. Opioids do not cause ACS but they can exacerbate hypoxia in patients with ACS. Morphine sulphate is the commonest strong opioid to start with.

E-9-1-1 126

E-9-1-1 ACS OR ICU 126

ACEP Now

FEBRUARY 11, 2025

Investigation of the adrenergic and opioid binding affinities, metabolic stability, plasma protein binding properties, and functional effects of selected indole-based kratom alkaloids. Kruegel AC, Gassaway MM, Kapoor A, et al. Gold MS, Pottash AC. Obeng S, Kamble SH, Reeves ME, et al. J Med Chem. 2020;63(1):433-439.

NARCAN 89

NARCAN Naloxone Overdose Mental Health Services 89

Dr. Smith's ECG Blog

FEBRUARY 6, 2025

Whenever I see PVCs with the morphology and axis seen in todays case I always look for signs of AC ( Arrhythmogenic Cardiomyopathy ). See this case for an in-depth discussion of AC and an example of VT and ECG changes associated with this disorder. The minimum effective plasma concentration of flecainide is about 200 ng/mL.

Plasma 73

Plasma ACS OR Coronary 73

EMDocs

JANUARY 6, 2025

link] Hummell AC, Cummings M. GI symptoms, right upper quadrant abdominal pain, jaundice. ^ = AMB, a region of sub-Saharan Africa consisting of > 20 countries which have an unusually high incidence of bacterial meningitis and frequency of outbreaks; nearly half of global bacterial meningitis cases occur in the AMB. Accessed June 11, 2023.

ED 73

ED E-9-1-1 ALS Emergency Department 73