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Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactionsAllergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%
We dont give solumedrol for allergicreactions anymore. Im sixty-six years old now and sometimes I must consult the protocols before I give a drug to make certain I am following the latest guidelines. Norepinephrine is now our go-to-vasopressor. I have to put my glasses on to read the protocols.
Anaphylaxis and Allergic ReactionsAnaphylaxis is a severe life-threatening allergicreaction affecting the entire body. Anaphylaxis is becoming more common and you may know someone with a severe allergy.
Anaphylactic Shock is an acute, life-threatening hypersensitivity disorder, with a generalized, rapidly evolving, multi-systemic allergicreaction (IgE-mediated disorder). If not treated rapidly can become fatal.
Here's what you can expect Unit 1 CPR How to communicate with patients How to provide accurate documentation Vital Signs Unit 2 Airway Management Respiratory emergencies Cardiac emergencies Unit 3 Neurological emergencies like seizures, strokes, drugs, alcohol, and behavioral emergencies Immunological emergencies (allergicreactions) Abdominal Pain (..)
Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactionsAllergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%
The nanotechnological approach renders the treatment much safer, as previous attempts to use stem cell factor as a pro-angiogenic treatment have been hampered by severe allergicreactions in some recipients. This latest technology helps to unlock the potential of the regenerative treatment. Via: University of Texas at Austin.
Do you pretreat the patient prior to CT scan or proceed without delay and risk an allergicreaction? Administer the pretreatment medications as this should prevent any severe allergicreaction. However, the patient tells you she has a history of IV contrast allergy.
Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergicreaction. Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergicreaction. Understanding the cause of angioedema (mast cell vs. bradykinin mediated) helps dictate directed management.
Most often occurs in uncircumcised males [Assim 2022] Buildup of sloughed and dead skin, microorganisms, and secretions between the foreskin and the glans Incidence in children shown to range from 0.05% up to 20% [Kayaba 1996, Hsieh 2006] Between 6% and 20% in uncircumcised men [Assim 2022, Perkins 2024] Pediatrics usually presents between 2y and 5y (..)
It’s a severe, potentially life-threatening allergicreaction that can occur within minutes. Anaphylaxis is a word that strikes fear in the hearts of many. For those who have experienced it—or… The post Navigating Anaphylaxis: Causes, Symptoms, and Treatment appeared first on Paramedics World.
In this month's EM Quick Hits podcast: Justin Morgenstern on the first RCT of high dose nitroglycerin in SCAPE, Andrew Neill on Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) indications and evidence, Brit Long on indications for CT in suspected diverticulitis, Tahara Bhate on Central Retinal Artery Occlusion (CRAO) and diagnostic (..)
Biphasic anaphylaxis: A review of the literature and implications for emergency management Corticosteroids in management of anaphylaxis; a systematic review of evidence
Platelets, like any blood product, are associated significant risks, not limited to acute lung injury, transfusion-related circulatory overload, allergicreactions, and more.
Sent by anonymous, written by Pendell Meyers A man in his late 40s presented to the ED with concern for allergicreaction after accidentally eating a potential allergen, then developing an itchy full body rash and diarrhea. In the ED he received methylprednisolone, diphenhydramine, and epinephrine for possible anaphylaxis.
Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergicreactions. Diphenhydramine versus nonsedating antihistamines for acute allergicreactions: a literature review. Resources: Banerji A, Long AA, Camargo CA Jr. Allergy Asthma Proc. Ledford, D.
Primary PCI: 95.7% Stents Placed: Pharmaco-Invasive Treatment: 97.4% Primary PCI: 95.7% ECG Results: Repeat ECG 90min after tenecteplase indicated 70.3% of patients in the pharmaco-invasive treatment achieved ≥50% resolution in the lead with the greatest ST-segment elevation Median decline from 3.0 Primary PCI: 78.4% Primary PCI: 13.3%
Incidence of clinically important biphasic reactions in emergency department patients with allergicreactions or anaphylaxis. Time of Onset and Predictors of Biphasic Anaphylactic Reactions: A Systematic Review and Meta-analysis.
Dilation of conjunctival vessels resulting in hyperemia and edema (A) is the underlying pathophysiology of conjunctivitis, which can be brought on by infection or allergicreaction. Close follow-up within 48 hours with an ophthalmologist is appropriate for ongoing monitoring and care.
Medical emergencies can vary, from heart attack to accidents to allergicreactions and more. If you want to learn more about dealing with medical emergencies safely and efficiently, check out this guide on medical emergency training here. What are the different types of medical emergencies?
Hypersensitivity/dermatologic: GLP-1 agonists are synthetic peptides; may lead to antibody formation and allergicreaction/injection site reaction. Reactions are usually minor: transient warmth, pruritis at injection site that resolves.
This information is crucial in avoiding allergicreactions, especially when administering emergency treatments. Allergies : Allergies can significantly impact how a patient responds to medication or environmental factors. EMTs must inquire about any known allergies, particularly to medications, foods, or environmental triggers.
This includes providing life-saving epinephrine to a patient having an allergicreaction, splinting a patient’s wounds following a car accident, or even performing CPR on a person experiencing cardiac arrest. EMTs are skilled at evaluating patients to see if any potentially fatal injuries or illnesses exist.
Those instances include the following: The person’s condition appears to be life-threatening — for example, the person is unconscious, bleeding profusely, choking, not breathing, or experiencing a severe allergicreaction. The person’s condition may become life-threatening on the way to the hospital.
Table 1: Comparison of F(ab) and F(ab’) 2 antivenoms. 9 This effect may be especially prominent in the setting of rattlesnake envenomation, where coagulopathic effects are more prominent.
These steroids are undoubtedly part of the cocktail we reach for in patients presenting with acute asthma, allergicreactions, or anaphylaxis - and traditional clinical logic has taught us these drugs work to reduce inflammation in the airways and reduce bronchial mucus production. Namely, Solumedrol and Dexamethasone (Decadron).
10 This procedure has well-described rare complications including infection, blood loss, allergicreaction, arrhythmia, pneumothorax if approaching via the internal jugular vein, embolization of the device, and pulmonary artery perforation or dissection. 8 The device itself is 2 x 2.5
What They Did: Parallel, 2-arm, noninferiority, open-label, multicenter, international randomized clinical trial Occurred in 6 specialized centers (3 in North America – US & Canada and 3 Outside of North America – Australia) Trial took place from June 2021 to December 2022 Used PEN-FAST to risk stratify patients.
An understanding of the risks involved including allergicreaction, radiation exposure, contrast extravasation, and contrast-associated nephropathy allows for a thorough risk-benefit analysis prior to ordering these studies. References (1) Barkovich, E.
There is a need to right size testing such that we do not miss clinically important PEs without exposing very low risk patients to risks of imaging (ionizing radiation, contrast, allergicreaction, cost, and misdiagnosis).
Answer : Leukopenia Overview Leukopenia is defined as total WBC count < 4000/mm 3 Neutropenia is the most common subset of leukopenia and is defined on absolute neutrophil count: 1 Mild (1.01.5 10^9/L) Moderate (0.50.9 10^9/L) Severe (< 0.5 10^9/L) Generalized leukopenia (i.e. Most common causes of leukopenia Infections: 36.4%
. “111 years of allergen-immunotherapy: a long and successful history of the only available disease-modifier in allergic diseases.” FDA approves first medication to help reduce allergicreactions to multiple foods after accidental exposure. ” Allergologie select 6 (2022): 248. Feb 16, 2024. FDA News Release.
Sometimes it seems like the world is out to get us: bees in our garden, pollen in the air, nuts in our brownies, any number of other things that could trigger an allergicreaction ranging from itchy eyes and a runny nose all the way to anaphylaxis. In the first episode of our two-parter on allergies, we explore that very question.
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