article thumbnail

REBEL Core Cast 108.0 – Angioedema

REBEL EM

Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. Read More EMCrit: Podcast 145 – Awake Intubation Lecture from SMACC ERCast: Angioedema References: Baş M et al.

article thumbnail

Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

REBEL EM

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Article: Abella BS et al. Diphenhydramine versus nonsedating antihistamines for acute allergic reactions: a literature review. Zuberbier, Torsten, et al. Ledford, D.

professionals

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

STREAM-2: Half-Dose Tenecteplase vs Primary PCI in Older Patients with STEMI?

REBEL EM

Paper: Van de Werf, F et al. References: Van de Werf, F et al. PMID: 37439219 Armstrong P et al. Based on this, the authors did a literature review and found that there is an increasing rate of ICH and major non-intracranial bleeding starting at ≈60 years of age. Primary PCI: 95.7% Stents Placed: Pharmaco-Invasive Treatment: 97.4%

STEMI 138
article thumbnail

Clinical Conundrums: How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis?

REBEL EM

Incidence of clinically important biphasic reactions in emergency department patients with allergic reactions or anaphylaxis. Time of Onset and Predictors of Biphasic Anaphylactic Reactions: A Systematic Review and Meta-analysis. The American Journal of Emergency Medicine 2018 Aug;36(8):1480-1485 Shaker M, et al.

article thumbnail

emDOCs Podcast – Episode 94: GLP-1 Agonist Complications

EMDocs

Hypersensitivity/dermatologic: GLP-1 agonists are synthetic peptides; may lead to antibody formation and allergic reaction/injection site reaction. Reactions are usually minor: transient warmth, pruritis at injection site that resolves. Shetty R, Basheer FT, Poojari PG, et al. Front Endocrinol (Lausanne).

article thumbnail

EM@3AM: Traumatic Iritis

EMDocs

Dilation of conjunctival vessels resulting in hyperemia and edema (A) is the underlying pathophysiology of conjunctivitis, which can be brought on by infection or allergic reaction. Lu, Kevin, et al. Close follow-up within 48 hours with an ophthalmologist is appropriate for ongoing monitoring and care. Traumatic Iritis.”

EMS 81
article thumbnail

Are Steroids really slow to act?

FOAMfrat

These steroids are undoubtedly part of the cocktail we reach for in patients presenting with acute asthma, allergic reactions, or anaphylaxis - and traditional clinical logic has taught us these drugs work to reduce inflammation in the airways and reduce bronchial mucus production. Namely, Solumedrol and Dexamethasone (Decadron).