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REBEL Core Cast 108.0 – Angioedema

REBEL EM

Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. Features Urticaria and pruritis Rapid onset (1-2 hours) IgE Dependent (Type I Hypersensitivity) Reactions An allergen cross-links two or more IgE molecules on mast cells or basophils and initiates a signal cascade leading to degranulation.

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Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

REBEL EM

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Article: Abella BS et al. Patients were randomized in a 1:1 ratio. Diphenhydramine versus nonsedating antihistamines for acute allergic reactions: a literature review.

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CT Angiography Head and Neck: Indications and Limitations

EMDocs

1 One study found that CTA head and neck was ordered for 2.5% 2 Outcomes of patients presenting with ischemic stroke who received MRI as initial imaging modality have demonstrated similar outcomes to those with initial CTA, with Kim et al. In a study of 17,903 CTAs ordered in the ED, Tu et al. 8 The data in Mayer et al.

E-9-1-1 105
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EM@3AM: Leukopenia

EMDocs

Answer : Leukopenia Overview Leukopenia is defined as total WBC count < 4000/mm 3 Neutropenia is the most common subset of leukopenia and is defined on absolute neutrophil count: 1 Mild (1.01.5 10^9/L) Moderate (0.50.9 10^9/L) Severe (< 0.5 10^9/L) Generalized leukopenia (i.e. 10^9/L) Moderate (0.50.9

E-9-1-1 94
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Episode 161 Allergies Part 1: Pollens, nuts, & bugs

This Podcast Will Kill You

Sometimes it seems like the world is out to get us: bees in our garden, pollen in the air, nuts in our brownies, any number of other things that could trigger an allergic reaction ranging from itchy eyes and a runny nose all the way to anaphylaxis. Allen, Judith E., Allergy and allergic diseases. Hurley, Sadhbh, et al.

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Episode 162 Allergies Part 2: Shots, pills, & pens

This Podcast Will Kill You

Cataldi, Mauro, et al. Journal of Allergy and Clinical Immunology, 141(1), pp.1-9. World Allergy Organization Journal, 1, pp.S18-S26. ” Clinical & Experimental Allergy 29 (1999): 1-11. Gutermuth, Jan, et al. Development of neffy, an Epinephrine Nasal Spray, for Severe Allergic Reactions.