Allergic Reaction, ALS and OR

REBEL Core Cast 108.0 – Angioedema

REBEL EM

SEPTEMBER 13, 2023

Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. Features Urticaria and pruritis Rapid onset (1-2 hours) IgE Dependent (Type I Hypersensitivity) Reactions An allergen cross-links two or more IgE molecules on mast cells or basophils and initiates a signal cascade leading to degranulation.

Frozen Plasma

Frozen Plasma Allergic Reaction FFP Plasma

STREAM-2: Half-Dose Tenecteplase vs Primary PCI in Older Patients with STEMI?

REBEL EM

SEPTEMBER 28, 2023

Paper: Van de Werf, F et al. The STREAM-1 trial found that for [2] patients with STEMI presenting within 3 hours of symptom onset and unable to attain PCI within 1 hour of first medical contact, a pharmaco-invasive strategy resulted in similar rates of death, shock, heart failure, or reinfarction compared to primary PCI.

STEMI

STEMI Allergic Reaction Coronary Ambulance

emDOCs Podcast – Episode 94: GLP-1 Agonist Complications

EMDocs

FEBRUARY 7, 2024

Hypersensitivity reaction to a GLP-1 agonist, type 1 diabetes mellitus, and pregnancy. Hypersensitivity/dermatologic: GLP-1 agonists are synthetic peptides; may lead to antibody formation and allergic reaction/injection site reaction. Reactions are usually minor: transient warmth, pruritis at injection site that resolves.

Allergic Reaction

Allergic Reaction ALS CAD OR

Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

REBEL EM

JANUARY 23, 2023

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Article: Abella BS et al. Moreover, the FDA approved intravenous (IV) cetirizine to treat acute urticaria in 2019. Ann Emerg Med 2020. in the IV cetirizine group and 2.1

Allergic Reaction

Allergic Reaction ED E-9-1-1 Emergency Department

Clinical Conundrums: How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis?

REBEL EM

DECEMBER 5, 2023

The overall incidence of biphasic reactions is unknown with rates quoted from < 0.5% This varied incidence can be due to inconsistent definitions or inclusion of mild reactions. Since half of biphasic reactions occur within the first 6-12 hrs ( Lee 2014 ) physicians often choose an observation time of 4-6 hrs. Read More: 1.

Epinephrine

Epinephrine Allergic Reaction Emergency Department Emergency Management

EM@3AM: Traumatic Iritis

EMDocs

JUNE 8, 2024

Dilation of conjunctival vessels resulting in hyperemia and edema (A) is the underlying pathophysiology of conjunctivitis, which can be brought on by infection or allergic reaction. Lu, Kevin, et al. Answer : Traumatic Iritis Epidemiology: There are approximately 55 million eye injuries worldwide annually. [1] UpToDate , 30 Oct.

EMS

EMS Allergic Reaction Emergency Department ED

ToxCard: Crotalid Envenomation Part 2 – CroFab vs. AnaVip: What’s the Difference?

EMDocs

AUGUST 31, 2023

Background Crotalidae ovine polyvalent immune F(ab) (CroFab®) is the most widely available crotalid antivenom in the United States and is approved for severe crotalid envenomation with severe or progressive localized symptoms, systemic toxicity, and signs of hematologic toxicity on labs. Table 1: Comparison of F(ab) and F(ab’) 2 antivenoms.

Allergic Reaction

Allergic Reaction Plasma ALS EMS

Are Steroids really slow to act?

FOAMfrat

FEBRUARY 18, 2024

These steroids are undoubtedly part of the cocktail we reach for in patients presenting with acute asthma, allergic reactions, or anaphylaxis - and traditional clinical logic has taught us these drugs work to reduce inflammation in the airways and reduce bronchial mucus production. Namely, Solumedrol and Dexamethasone (Decadron).

Allergic Reaction

Allergic Reaction OR ALS ED

What the Emergency Clinician Must Know about Remote Monitors in Heart Failure

EMDocs

JANUARY 3, 2024

10 This procedure has well-described rare complications including infection, blood loss, allergic reaction, arrhythmia, pneumothorax if approaching via the internal jugular vein, embolization of the device, and pulmonary artery perforation or dissection. Optivol TM , measures thoracic impedance through an ICD or CRT-D device.

Defibrillator

Defibrillator Allergic Reaction ED ALS

The PALACE Trial: Direct Oral PCN Challenge in Patients with Low-Risk PCN Allergy?

REBEL EM

AUGUST 3, 2023

Paper: Copaescu AM et al. This practice is both resource and time intensive thus limiting the number of people who can actually have their penicillin allergy removed from their chart. A rapid, safe approach to confirming or refuting allergies is needed. JAMA Intern Med 2023. randomization) as per protocol (i.e.

Allergic Reaction

Allergic Reaction OR ALS Emergency Department

CT Angiography Head and Neck: Indications and Limitations

EMDocs

NOVEMBER 13, 2023

2 Outcomes of patients presenting with ischemic stroke who received MRI as initial imaging modality have demonstrated similar outcomes to those with initial CTA, with Kim et al. In a study of 17,903 CTAs ordered in the ED, Tu et al. 8 The data in Mayer et al. 9 A later assessment of the VAN score in Beume et al.

E-9-1-1

E-9-1-1 ALS Emergency Department ED

SGEM#469: You Take My Breath Away – D-dimer for Ruling out PE in High-Risk Patients

The Skeptics' Guide to EM

MARCH 1, 2025

Reference: Bannelier et al. There is a need to right size testing such that we do not miss clinically important PEs without exposing very low risk patients to risks of imaging (ionizing radiation, contrast, allergic reaction, cost, and misdiagnosis). Reference: Bannelier et al.

Allergic Reaction

Allergic Reaction ALS Emergency Department ED

EM@3AM: Leukopenia

EMDocs

JANUARY 25, 2025

Well keep it short, while you keep that EM brain sharp. A previously healthy 23-year-old male with no medical or surgical history presents to the ED with generalized malaise and no energy, progressively getting worse over the last six weeks. 10^9/L) Moderate (0.50.9 10^9/L) Severe (< 0.5 10^9/L) Generalized leukopenia (i.e. Medications: 25.6%

E-9-1-1

E-9-1-1 EMS Allergic Reaction ED

Episode 162 Allergies Part 2: Shots, pills, & pens

This Podcast Will Kill You

JANUARY 14, 2025

Cataldi, Mauro, et al. Gutermuth, Jan, et al. “111 years of allergen-immunotherapy: a long and successful history of the only available disease-modifier in allergic diseases.” FDA approves first medication to help reduce allergic reactions to multiple foods after accidental exposure. 2015): 350-351. .”

Allergic Reaction

Allergic Reaction E-9-1-1 Epinephrine ALS

Paramedicine Now

REBEL Core Cast 108.0 – Angioedema

STREAM-2: Half-Dose Tenecteplase vs Primary PCI in Older Patients with STEMI?

Trending Sources

emDOCs Podcast – Episode 94: GLP-1 Agonist Complications

Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

Clinical Conundrums: How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis?

EM@3AM: Traumatic Iritis

ToxCard: Crotalid Envenomation Part 2 – CroFab vs. AnaVip: What’s the Difference?

Are Steroids really slow to act?

What the Emergency Clinician Must Know about Remote Monitors in Heart Failure

The PALACE Trial: Direct Oral PCN Challenge in Patients with Low-Risk PCN Allergy?

CT Angiography Head and Neck: Indications and Limitations

SGEM#469: You Take My Breath Away – D-dimer for Ruling out PE in High-Risk Patients

EM@3AM: Leukopenia

Episode 162 Allergies Part 2: Shots, pills, & pens

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