Allergic Reaction ALS Plasma 
REBEL EM
SEPTEMBER 13, 2023
Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. Without the C1 inhibitor, the plasma-kallikrein-kinin system produces more bradykinin. Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. PMID 25629740 Hassen GW et al.
EMDocs
AUGUST 31, 2023
Plasma half-life of the F(ab’) 2 antivenom is significantly longer at 5.5 Bush SP, Ruha AM, Seifert SA, et al. link] Kanaan NC, Ray J, Stewart M, et al. F(ab) is smaller, consisting of a single antigen binding site, while F(ab’) 2 consists of two antigen-binding sites linked together by an antibody “hinge” region. 5 Figure 1.
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