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Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergicreactions. Key Secondary Endpoints: 5 (3.9%) patients in the IV cetirizine group returned to any ED or clinic within 24 hours compared to 15 (11.1%) in the IV diphenhydramine group; P=0.04
Sent by anonymous, written by Pendell Meyers A man in his late 40s presented to the ED with concern for allergicreaction after accidentally eating a potential allergen, then developing an itchy full body rash and diarrhea. In the ED he received methylprednisolone, diphenhydramine, and epinephrine for possible anaphylaxis.
The risk of a biphasic reaction is what keeps patients in the ED while being observed for a set period of time. The overall incidence of biphasic reactions is unknown with rates quoted from < 0.5% This varied incidence can be due to inconsistent definitions or inclusion of mild reactions.
These steroids are undoubtedly part of the cocktail we reach for in patients presenting with acute asthma, allergicreactions, or anaphylaxis - and traditional clinical logic has taught us these drugs work to reduce inflammation in the airways and reduce bronchial mucus production. Basic & clinical pharmacology (12th ed.).
The use of CTA (computed tomography angiography) in the emergency department (ED) has increased dramatically in the past 20 years. of all patients in the ED for over 800 different stated indications. 5, 6 Further, any use of imaging prolongs ED stays, which by extension increases ED wait times for other patients.
A previously healthy 23-year-old male with no medical or surgical history presents to the ED with generalized malaise and no energy, progressively getting worse over the last six weeks. In: Newburger P, Rosmarin AG, eds. Well keep it short, while you keep that EM brain sharp. 10^9/L) Moderate (0.50.9 10^9/L) Severe (< 0.5
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