REBEL EM

DECEMBER 5, 2023

The overall incidence of biphasic reactions is unknown with rates quoted from < 0.5% This varied incidence can be due to inconsistent definitions or inclusion of mild reactions. Since half of biphasic reactions occur within the first 6-12 hrs ( Lee 2014 ) physicians often choose an observation time of 4-6 hrs.

Epinephrine 81

Epinephrine Allergic Reaction Emergency Department Emergency Management 81

REBEL EM

JANUARY 23, 2023

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Diphenhydramine versus nonsedating antihistamines for acute allergic reactions: a literature review. Multicenter study of emergency department visits for insect sting allergies.

Allergic Reaction 52

Allergic Reaction ED E-9-1-1 Emergency Department 52

REBEL EM

AUGUST 3, 2023

What They Did: Parallel, 2-arm, noninferiority, open-label, multicenter, international randomized clinical trial Occurred in 6 specialized centers (3 in North America – US & Canada and 3 Outside of North America – Australia) Trial took place from June 2021 to December 2022 Used PEN-FAST to risk stratify patients.

Allergic Reaction 52

Allergic Reaction OR ALS Emergency Department 52

EMDocs

NOVEMBER 13, 2023

The use of CTA (computed tomography angiography) in the emergency department (ED) has increased dramatically in the past 20 years. 63 This is because their definition of CI-AKI is an AKI that ensues within 48 hours of receiving IV contrast in the absence of any “other nephrotoxic factors.” References (1) Barkovich, E. .;

E-9-1-1 105

E-9-1-1 ALS Emergency Department ED 105

EMDocs

JANUARY 25, 2025

Specific Considerations: Neutropenic Fever: 15 Definition: Absolute Neutrophil Count <500 or <1000 with predicted nadir of <500 in 48 hours AND Fever 38.3C (101F) or a temperature of 38.0C (100.4F) sustained over a one-hour period Treatment: Inpatient: Cefepime 2g IV q8hrs OR Meropenem 1g IV q8hrs OR Piperacillin/Tazobactam 4.5g

E-9-1-1 96

E-9-1-1 EMS Allergic Reaction ED 96