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Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

REBEL EM

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Patients were randomized in a 1:1 ratio. Anecdotally, the persistence of urticaria often has little influence on the decision to discharge a patient from the ED.

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Anaphylaxis, chest pain, and ST elevation in aVR

Dr. Smith's ECG Blog

Sent by anonymous, written by Pendell Meyers A man in his late 40s presented to the ED with concern for allergic reaction after accidentally eating a potential allergen, then developing an itchy full body rash and diarrhea. In the ED he received methylprednisolone, diphenhydramine, and epinephrine for possible anaphylaxis.

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REBEL Core Cast 108.0 – Angioedema

REBEL EM

Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. Features Urticaria and pruritis Rapid onset (1-2 hours) IgE Dependent (Type I Hypersensitivity) Reactions An allergen cross-links two or more IgE molecules on mast cells or basophils and initiates a signal cascade leading to degranulation.

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CT Angiography Head and Neck: Indications and Limitations

EMDocs

The use of CTA (computed tomography angiography) in the emergency department (ED) has increased dramatically in the past 20 years. 1 One study found that CTA head and neck was ordered for 2.5% of all patients in the ED for over 800 different stated indications. In a study of 17,903 CTAs ordered in the ED, Tu et al.

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