Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED
REBEL EM
JANUARY 23, 2023
Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Key Secondary Endpoints: 5 (3.9%) patients in the IV cetirizine group returned to any ED or clinic within 24 hours compared to 15 (11.1%) in the IV diphenhydramine group; P=0.04
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