Core EM

OCTOBER 16, 2024

Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3% In: Marx J, ed. Br J Haematol.

Allergic Reaction 188

Allergic Reaction Plasma ED Epinephrine 188

REBEL EM

SEPTEMBER 13, 2023

Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. Without the C1 inhibitor, the plasma-kallikrein-kinin system produces more bradykinin. Understanding the cause of angioedema (mast cell vs. bradykinin mediated) helps dictate directed management.

Frozen Plasma 105

Frozen Plasma Allergic Reaction FFP Plasma 105

Core EM

OCTOBER 2, 2024

Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3% In: Marx J, ed. Br J Haematol.

Allergic Reaction 100

Allergic Reaction Plasma ED Epinephrine 100