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Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactionsAllergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%
Anaphylactic Shock is an acute, life-threatening hypersensitivity disorder, with a generalized, rapidly evolving, multi-systemic allergicreaction (IgE-mediated disorder). If not treated rapidly can become fatal.
How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis? Bottom Line Up Top: After prompt recognition and appropriate treatment with IM epinephrine, the risk of biphasic reactions are exceedingly low. At the time of discharge, appropriate patient education and prescriptions for IM epinephrine are essential.
Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactionsAllergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%
Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergicreaction. Features Urticaria and pruritis Rapid onset (1-2 hours) IgE Dependent (Type I Hypersensitivity) Reactions An allergen cross-links two or more IgE molecules on mast cells or basophils and initiates a signal cascade leading to degranulation.
Sent by anonymous, written by Pendell Meyers A man in his late 40s presented to the ED with concern for allergicreaction after accidentally eating a potential allergen, then developing an itchy full body rash and diarrhea. In the ED he received methylprednisolone, diphenhydramine, and epinephrine for possible anaphylaxis.
Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergicreactions. antibiotics, NSAIDs) Acute urticaria with angioedema or anaphylaxis provided that urticaria was still present after initial treatment and alleviation of anaphylaxis symptoms.
This includes providing life-saving epinephrine to a patient having an allergicreaction, splinting a patient’s wounds following a car accident, or even performing CPR on a person experiencing cardiac arrest. Thinking about the paramedic vs. EMT debate? It’s not just you. It never gets dull!
Our allergy treatment toolkit includes an impressive suite of tools, and in the second episode of our two-part series on allergies, we focus on three in particular: antihistamine medications, allergy shots, and the epinephrine auto-injector (aka the EpiPen). “Epinephrine: a short history.” Then this is the episode for you.
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