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Transfusion Reactions

Core EM

Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%

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Transfusion Reactions

Core EM

Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%

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Lipid Nanodiscs Unlock the Potential of Cytokine Treatment

Medgadget

The nanotechnological approach renders the treatment much safer, as previous attempts to use stem cell factor as a pro-angiogenic treatment have been hampered by severe allergic reactions in some recipients. Regenerative medicine holds enormous potential in treating patients who have suffered tissue damage after a cardiovascular event.

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REBEL Core Cast 108.0 – Angioedema

REBEL EM

Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. Understanding the cause of angioedema (mast cell vs. bradykinin mediated) helps dictate directed management.

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Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

REBEL EM

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. T5 (3.9%) patients with adverse events were reported in the IV Cetirizine group compared to 18 (3.9%) in the IV diphenhydramine group. in the IV cetirizine group and 2.1 PMID: 17883909.

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emDOCs Podcast – Episode 94: GLP-1 Agonist Complications

EMDocs

GLP-1 agonists are also associated with improved ejection fraction, coronary blood flow, and cardiac output while reducing the risk of cardiovascular events, infarction size, and all-cause mortality. Adverse events are common in those using GLP-1 agonists, but the vast majority of these are minor. Take for example semaglutide.

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EMT Essentials: Mastering SAMPLE History and OPQRST Pain Assessment Techniques

EMT Training Station

This information is crucial in avoiding allergic reactions, especially when administering emergency treatments. Events Leading Up to the Present Illness/Injury : The circumstances surrounding the onset of the patient’s current condition can offer valuable clues about the nature of the emergency.

EMT 96