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Transfusion Reactions

Core EM

Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%

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Transfusion Reactions

Core EM

Author: Natalie Bertrand, MD Editor: Naillid Felipe, MD Background: Definition: adverse reaction to blood product administration Incidence: more common in children than adults, except for delayed hemolytic transfusion reactions Allergic (non-anaphylaxis) – Platelets 1-3%; RBCs 0.1-0.3%

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Navigating Anaphylaxis: Causes, Symptoms, and Treatment

Paramedics World

It’s a severe, potentially life-threatening allergic reaction that can occur within minutes. Anaphylaxis is a word that strikes fear in the hearts of many. For those who have experienced it—or… The post Navigating Anaphylaxis: Causes, Symptoms, and Treatment appeared first on Paramedics World.

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Clinical Conundrums: Should I Pretreat Patients with Contrast Allergy Prior to IV Contrast Administration?

REBEL EM

Do you pretreat the patient prior to CT scan or proceed without delay and risk an allergic reaction? Administer the pretreatment medications as this should prevent any severe allergic reaction. However, the patient tells you she has a history of IV contrast allergy.

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Steroid and Allergy

Emergency Medicine Education

Biphasic anaphylaxis: A review of the literature and implications for emergency management Corticosteroids in management of anaphylaxis; a systematic review of evidence

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Lipid Nanodiscs Unlock the Potential of Cytokine Treatment

Medgadget

The nanotechnological approach renders the treatment much safer, as previous attempts to use stem cell factor as a pro-angiogenic treatment have been hampered by severe allergic reactions in some recipients. This latest technology helps to unlock the potential of the regenerative treatment. Via: University of Texas at Austin.

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Toss Up: A Little Bleeding, or A Lot of Platelets

EM Literature of Note

Platelets, like any blood product, are associated significant risks, not limited to acute lung injury, transfusion-related circulatory overload, allergic reactions, and more.