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emDOCs Podcast – Episode 81: Hemophilia

EMDocs

The patient’s plasma is mixed with normal pooled plasma (NPP) which adds sufficient clotting factors to overcome the deficiency. If an inhibitor is present, it will inhibit the clotting factors in patient plasma and the NPP, and the clotting time remains prolonged. Each unit of FVIII/kg raises the plasma FVIII level by 2%.

Plasma 75
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Spicy Bites - Snake Envenomation

FOAMfrat

Along with inducing coagulopathy, venom toxins may contribute to local and/or systemic hemorrhage and plasma extravasation by means of basement membrane degradation within the vasculature. The date and time the bite occurred as well as a physical description of the snake should be documented. PubMed , StatPearls Publishing, 13 Mar.

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Case Report: Toxic Hypoglycemic Syndrome

ACEP Now

4 The association between ackee ingestion and the illness was initially recognized in 1875 and officially documented in 1904. 5 Despite being endemic to Jamaica, cases of THS have been reported across the world, with the first case in the United States documented in 1993. References Katibi OS, Olaosebikan R, et al. Clin Toxicol.

Plasma 40
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Patient with severe DKA, look at the ECG

Dr. Smith's ECG Blog

Document in the patient's chart that rapid infusion is intentional in response to life-threatening hypokalemia." mEq/L, the associated loss is double, at 200-400 mEq.* [ Sterns RH, et al. Internal potassium balance and the control of the plasma potassium concentration. "If cardiac arrest from hypokalemia is imminent (i.e.,

Plasma 52
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Profound ST depression in II, III, aVF

Dr. Smith's ECG Blog

Peak plasma concentration of amphetamines is rapid ( within minutes ) following inhalation or injection. PEARL #3: The pathophysiologic mechanism for producing amphetamine-induced acute MI is unclear ( Bazmi et al — SQUMJ 17(10); e31-37, 2017 — and — Sinha et al — Case Rep Cardiol, 2016 ).

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STEMI with Life-Threatening Hypokalemia and Incessant Torsades de Pointes

Dr. Smith's ECG Blog

Document in the patient's chart that rapid infusion is intentional in response to life-threatening hypokalemia." the associated loss is double, at 200-400 mEq.* [ Sterns RH, et al. Internal potassium balance and the control of the plasma potassium concentration. "If cardiac arrest from hypokalemia is imminent (i.e., mmol/L).

STEMI 52
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Popular Antiobesity Medications Bring New Challenges to Emergency Physicians

ACEP Now

There have been documented cases of overdose, and of note, there is no known antidote. Sodhi M, Rezaeianzadeh R, Kezouh A, et al. Ahmann AJ, Capehorn M, Charpentier G, et al. Bansal AB, Al Khalili Y. Semaglutide has a half-life of approximately one week; as such, it is long-acting and requires supportive measures.