ALS Emergency Department Naloxone 
The Skeptics' Guide to EM
AUGUST 27, 2022
Date: August 23rd, 2022 Reference: Schoenfeld et al. AEM August 2022 Guest Skeptic: Dr. Chris Bond is an emergency medicine physician and assistant Professor at the University of Calgary. Date: August 23rd, 2022 Reference: Schoenfeld et al. He is successfully resuscitated using naloxone and is stable after an observation period.
ALiEM
NOVEMBER 29, 2023
Naloxone will not reverse the effects of xylazine; however, it is routinely given in unresponsive or obtunded patients presenting with an opioid toxidrome. In patients with minimal response to naloxone, xylazine toxicity may be suspected [10]. PMID: 34529640 Ayub S, Parnia S, Poddar K, et al. MMWR Morb Mortal Wkly Rep.
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ACEP Now
JULY 7, 2023
Emergency departments (EDs) focus on rapid initiation of medical treatment. Patients with opiate overdose get naloxone. References American College of Emergency Physicians Clinical Policies Subcommittee on the Adult Psychiatric P, Nazarian DJ, Broder JS, et al. Ann Emerg Med. West J Emerg Med.
REBEL EM
JUNE 5, 2023
One study from a county in Massachusetts found that of all nonfatal opioid doses seen in the emergency department from 2011-2015, 1 in 20 patients subsequently died within one year of initial visit with 66% of these deaths being directly related to an opioid overdose (4). mg SL BID One-half tablet 3 Buprenorphine 2 mg–naloxone 0.5
The Skeptics' Guide to EM
JANUARY 19, 2019
Date: January 17th , 2019 Reference: Clemency et al. Hospital Observation Upon Reversal (HOUR) With Naloxone: A Prospective Clinical Prediction Rule Validation Study. Date: January 17th , 2019 Reference: Clemency et al. Sixty minutes after receiving naloxone he is GCS 15 and walking to the desk demanding to be discharged.
ACEP Now
OCTOBER 15, 2023
1 The emergency department remains an important frontier for work in judicious prescribing, but opiate analgesia remains a valuable tool for the initial treatment of a variety of presentations. The addition of naloxone to the tablets may also provide a confounder in terms of the analgesia provided.
ACEP Now
DECEMBER 10, 2023
A middle-aged male with squamous cell carcinoma and extensive metastases is brought to the emergency department (ED) after being found unresponsive following a believed suicide attempt (SA) by methadone ingestion. Though paramedics administered naloxone, he remained somnolent. References Nowland R, Steeg S, Quinlivan L, et al.
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