Remove ALS Remove Epinephrine Remove Events
article thumbnail

Updates in High dose Insulin and Euglycemia Therapy (HIET) for the treatment of Beta-adrenergic Receptor and Calcium Channel Antagonists Overdose

Core EM

HIET improves contractility without increasing SVR, while vasopressin and epinephrine transiently increase SVR/MAP but worsen cardiac output in anesthetized dogs given propranolol (Holger 2007). References: Yuan TH, Kerns WP, Tomaszewski CA, et al. von Lewinski D, Bruns S, Walther S, et al. Disposition to ICU. Circulation.

Overdose 246
article thumbnail

Neurogenic Shock in Children

Pediatric EM Morsels

Pathophysiology Primary injury happens at the time of the traumatic event or shortly after in the high cervical to mid-thoracic spine. Both norepinephrine and epinephrine can be used. Epinephrine is key if there is significant bradycardia. Tenenbein M, Macias CG, Sharieff GQ, et al, eds. 5 th Edition. Neurogenic Shock.

E-9-1-1 300
professionals

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

POOs, LOOs, DOOs, and MOOs?

Don't Forget the Bubbles

However, it was still patient-oriented, considering the patient’s clinical response, symptom resolution, and adverse events. Disease-Oriented Outcomes (DOOs) The PARAMEDIC-2 trial looked at the effectiveness of epinephrine in adult patients who suffered an out-of-hospital cardiac arrest. Schuh S, Freedman S, Coates A, et al.

article thumbnail

SGEM#301: You Can’t Stop GI Bleeds with TXA

The Skeptics' Guide to EM

Reference: Roberts et al. Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. Audrey’s academic interests include trauma and resuscitation.

article thumbnail

Bubble Wrap PLUS – May 2024

Don't Forget the Bubbles

Dell KM, et al. Eisen S et al. Fielder AR, et al. Bm MV, et al. Toepfner N, et al. Toniutti M, et al. Meoli M, et al. Ashton JJ, et al. Ding G et al. Tanti DC, et al. Ahlqvist VH, et al. Chiang HL, et al. Wong J, et al. Fuller S et al. Koenis MM et al.

E-9-1-1 69
article thumbnail

ToxCard: Local Anesthetic Systemic Toxicity

EMDocs

While not specifically reviewed in this post, check out the methemoglobinemia tox card for more information about one of the other known events that can occur with local anesthetic administration. 1,2] Consider using a physiological marker to help identify inadvertent vascular injection, such as epinephrine. [3] BMJ Case Rep.

E-9-1-1 93
article thumbnail

The Safety and Efficacy of Push Dose Vasopressors in Critically Ill Adults

REBEL EM

1-4 The PDPs, phenylephrine and epinephrine, result in vasoconstriction and increased cardiac contractility. They can be associated with side effects such as reflex bradycardia, decreased stroke volume in phenylephrine, tachycardia and hypertension associated with epinephrine. Paper: Singer S, et al. Am J Emerg Med. 2022 Sep 5.