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SGEM#460: Why Do I Feel Like, Somebody’s Watching Me – CHARTWatch to Predict Clinical Deterioration

The Skeptics' Guide to EM

Date: October 28, 2024 Reference: Verma et al. Their hospital has struggled with a growing number of adverse events that often occur without warning. Reference: Verma et al. Clinical evaluation of a machine learning–based early warning system for patient deterioration.

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TXA (Tranexamic Acid) in Pediatrics 

Pediatric EM Morsels

Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion intrauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. PubMed: 22006852] Nishijima DK, VanBuren JM, Linakis SW, et al. 0000000000000075 Nishijima DK, Monuteaux MC, Faraoni D, et al. Acad Emerg Med.

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SGEM#428: Don’t Worry, Be Happy – The Safety of Nitroglycerin Administration in RVMI

The Skeptics' Guide to EM

Adverse events from nitrate administration during right ventricular myocardial infarction: a systematic review and meta-analysis. Adverse events from nitrate administration during right ventricular myocardial infarction: a systematic review and meta-analysis. Fanaroff et al looked at the ACC/AHA guidelines from 2008-2018 [4].

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SGEM#226: I Want A New Drug – One that Doesn’t Cause an Adverse Drug Event

The Skeptics' Guide to EM

[display_podcast] Date: August 16th, 2018 Reference: Hohl C et al. Prospective Validation of Clinical Criteria to Identify Emergency Department Patients at High Risk for Adverse Drug Events. display_podcast] Date: August 16th, 2018 Reference: Hohl C et al. Reference: Hohl C et al. AEM Aug 2018. AEM Aug 2018. AEM Aug 2018.

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The Kids THRIVE study: high-flow apnoeic oxygenation for intubation

Don't Forget the Bubbles

Thats exactly what Shane George et al. George S, Williams T, Humphreys S, et al. Primary outcomes The modified intention-to-treat analysis found no statistically significant difference between the nasal high-flow and standard care groups in reducing hypoxaemic events or improving first-attempt intubation success.

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Targeted Temperature Management in Paediatric Traumatic Brain Injury

Don't Forget the Bubbles

Kochanek et al. explored the evidence in a 2019 systematic review, which forms part of the Brain Trauma Foundation Guidelines, as did Utsumi et al. The guidelines by Kochanek et al. The most recent meta-analysis by Utsumi et al. 2022.01291 Kochanek PM, Tasker RC, Carney N, et al. Three secondary analyses.

ALS 117
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emDOCs Podcast – Episode 110: Primary Spontaneous Bacterial Peritonitis

EMDocs

Guidelines also recommend against routinely transfusing blood products to correct coagulation panel abnormalities; transfusion is associated with adverse events and does not reduce the risk of bleeding. Biggins SW, Angeli P, Garcia-Tsao G, et al. Mattos AA, Wiltgen D, Jotz RF, et al. Aithal GP, Palaniyappan N, China L, et al.

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