ALS and FFP - Paramedicine Now

Podcast 185.0: Anticoagulation Reversal

Core EM

JANUARY 25, 2024

Hosts: Joe Offenbacher, MD Audrey Bree Tse, MD [link] Download Leave a Comment Tags: Anticoagulation , Critical Care , Resuscitation Show Notes Coagulation Cascade: Algorithm for Anticoagulated Bleeding Patient in the ED: Indications for Anticoagulation Reversal: References: Baugh CW, Levine M, Cornutt D, et al. Ann Emerg Med.

Frozen Plasma

Frozen Plasma FFP Plasma Critical Care

Anticoagulation Reversal

Core EM

JANUARY 24, 2024

2017.09.1085 Gómez-Outes A, Alcubilla P, Calvo-Rojas G, et al. doi:10.1186/s13054-019-2492-8 Baugh CW, Levine M, Cornutt D, et al. 2019.09.001 Gilbert BW, Morton L, Huffman JB, et al. 2019.10.013 Patel IJ, Rahim S, Davidson JC, et al. 2019.04.017 Connolly SJ, Milling TJ Jr, Eikelboom JW, et al. J Am Coll Cardiol.

FFP

FFP Frozen Plasma Plasma ALS

REBEL Cast Ep 118: The PROCOAG Trial – 4F-PCC for Trauma Patients?

REBEL EM

JUNE 26, 2023

Click here for Direct Download of the Podcast Paper: Bouzat P et al. References: Bouzat P et al. PMID: 36942533 Innerhofer P et al. High-quality studies are needed to determine the utility of this intervention. REBEL Cast Ep118: The PROCOAG Trial – 4F-PCC in Trauma Patients? to 3.33; P = 0.72 to 2.10; P = 0.03

FFP

FFP Frozen Plasma ALS Plasma

REBEL Core Cast 108.0 – Angioedema

REBEL EM

SEPTEMBER 13, 2023

Read More EMCrit: Podcast 145 – Awake Intubation Lecture from SMACC ERCast: Angioedema References: Baş M et al. PMID 25629740 Hassen GW et al. PMID 23062323 Kostis JB et al. PMID 16043683 McCormick M et al. PMID 20954277 Sinnert R et al. Zuraw et al. N Engl J Med. 2015; 372(5):418-25. 2013;24:53-66.

Frozen Plasma

Frozen Plasma Allergic Reaction FFP Plasma

SGEM386: Blood on Blood – Massive Transfusion Protocols in Older Trauma Patients

The Skeptics' Guide to EM

DECEMBER 17, 2022

Date: December 16th, 2022 Reference: Hohle et al. Date: December 16th, 2022 Reference: Hohle et al. The transfusion tech calls to remind you that your protocol is currently under review, and asks if would you like the 1:1 or the 1:3 version of fresh-frozen plasma (FFP) to packed red blood cells (pRBC)? years ( 2 ).

Frozen Plasma

Frozen Plasma FFP Emergency Medical Services Plasma

CRYOSTAT-2: Early Empiric Cryoprecipitate in Major Trauma

REBEL EM

OCTOBER 30, 2023

Most major hemorrhage protocols give a balanced transfusion of PRBCs, FFP, and platelets in ratios approaching concentrations found in whole blood. Paper: Davenport R et al. References: Davenport R et al. Fibrinogen products may also be needed to stabilize clots and stem bleeding. Cryoprecipitate Group: 25.3% to 1.23; p = 0.74

FFP

FFP ALS OR EMS

Thrombotic Thrombocytopenic Purpura (TTP)

Core EM

JANUARY 25, 2024

Joly, 2017; Sawler, 2020) Fresh frozen plasma (FFP) (contains ADMTS-13) may be used to supplement ADAMTS-13 if there is a delay in initiating TPE in the emergency department (i.e. Scully, 2012) Citations: Balduini CL, et al. Paydary, Koosha, et al. Sawler D, Parker A, Britto J, et al. Ann Hematol. J Emerg Med.

Plasma

Plasma Frozen Plasma Emergency Department FFP

TEG-Guided Resuscitation of Patients with Cirrhosis and Non-Variceal Bleeding

REBEL EM

SEPTEMBER 26, 2022

A meta-analysis of fifteen RCTs comparing blood product transfusion rates of cardiothoracic and surgery patients found significantly lower transfusion rates of FFP in TEG/ROTEM guided group compared to traditional tests, with no difference in survival rates (Fahrendorff 2017). Article: Kumar M et al. Were these providers blinded?

FFP

FFP E-9-1-1 ICU ALS

emDOCs Podcast – Episode 102: Hypocalcemia in Trauma and the Diamond of Death

EMDocs

JUNE 12, 2024

FFP and platelets also contain citrate. Giancarelli et al found that 97% of patients who underwent massive transfusion protocols during trauma resuscitation were hypocalcemic (iCa < 1.1 Kyle et al demonstrated that transfusing a single unit of pRBCs can lead to significant decreases in Ca. Byerly S, Inaba K, Biswas S, et al.

ALS

ALS FFP Plasma Emergency Department

Best Practices for Upper Gastrointestinal Hemorrhage

ACEP Now

NOVEMBER 16, 2023

Fresh frozen plasma, or FFP, should only be given to cirrhotic patients as part of the massive transfusion protocol in cases of profound hypotension, as “patients with cirrhosis rarely have true enzymatic hypocoagulability, and FFP may worsen bleeding due to over-resuscitation and dilution of coagulation factors.” Am J Emerg Med.

Frozen Plasma

Frozen Plasma FFP ALS Plasma

EM@3AM: Amniotic Fluid Embolism

EMDocs

JUNE 22, 2024

” Obstet Gynecol 123(2 Pt 1): 337-348. link] Society for Maternal-Fetal Medicine. Electronic address, p. “Amniotic fluid embolism: diagnosis and management.” ” Am J Obstet Gynecol 215(2): B16-24. link] j.ajog.2016.03.012 2016.03.012 Patel, P., ” Clin Appl Thromb Hemost 25: 1076029619843338.

EMS

EMS Ambulance FFP ICU

Penetrating chest trauma

Don't Forget the Bubbles

JUNE 30, 2023

a) A balanced ratio of 1:1:1 (platelets: FFP: packed red cells) The PROPPR trial showed us that balanced ratios are important. b) A balanced ratio of 1: 1:2 (platelets: FFP: packed red cells) The PROPPR trial showed us that balanced ratios are important. Laan DV, Vu TD, Thiels CA et al. And blood comes out. Quite quickly.

E-9-1-1

E-9-1-1 FFP Plasma Emergency Department

Recognition and Treatment of Thrombotic Thrombocytopenic Purpura

ACEP Now

APRIL 5, 2024

Therapeutic plasma exchange (TPE) with fresh frozen plasma (FFP) is the first-line treatment, by simultaneously supplying fresh ADAMTS13 and removing anti-ADAMTS13 autoantibodies. References Sukumar S, Lämmle B, et al. Kessler CS, Khan BA, et al. Li XM, Mo XY, et al. 2021;46:556-9 Long B, Bridwell RE, et al.

Frozen Plasma

Frozen Plasma Plasma Emergency Department FFP

A guide to major haemorrhage management in paediatrics

Don't Forget the Bubbles

OCTOBER 28, 2024

Karageorgos S, Ren D, Ranaweera M, et al. Major haemorrhage protocols typically include a mixture of packed red blood cells (pRBCs), platelets, and fresh frozen plasma (FFP). Platelets and FFP replace lost platelets and coagulation factors, which help with clotting and also provide some volume expansion. Am J Emerg Med.

Frozen Plasma

Frozen Plasma FFP Plasma ALS

Paramedicine Now

Podcast 185.0: Anticoagulation Reversal

Anticoagulation Reversal

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REBEL Cast Ep 118: The PROCOAG Trial – 4F-PCC for Trauma Patients?

REBEL Core Cast 108.0 – Angioedema

SGEM386: Blood on Blood – Massive Transfusion Protocols in Older Trauma Patients

CRYOSTAT-2: Early Empiric Cryoprecipitate in Major Trauma

Thrombotic Thrombocytopenic Purpura (TTP)

TEG-Guided Resuscitation of Patients with Cirrhosis and Non-Variceal Bleeding

emDOCs Podcast – Episode 102: Hypocalcemia in Trauma and the Diamond of Death

Best Practices for Upper Gastrointestinal Hemorrhage

EM@3AM: Amniotic Fluid Embolism

Penetrating chest trauma

Recognition and Treatment of Thrombotic Thrombocytopenic Purpura

A guide to major haemorrhage management in paediatrics

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