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Clinical impact: Rather than arguing with the patient about the likelihood of this phenomenon occurring and whether this is a true allergy, the patient is informed that they do not need to immediately start treatment to receive care in the hospital. Multimodal medication options for fentanyl-xylazine withdrawal management in London et al.
The reality of ever increasing ED volumes and longer boarding times to the ICU makes it imperative for emergency physicians to learn how to manage these critical patients. It was found that patients exposed to deep sedation in the ED had an independent higher incidence of continued deep sedation on ICU day one ( Fuller, 2019 ).
Thats exactly what Shane George et al. George S, Williams T, Humphreys S, et al. Effectiveness of Nasal High-Flow Oxygen during apnoea on Hypoxaemia and Intubation Success in Paediatric Emergency and ICU Settings: a randomised, controlled, open-label trial. Lancet Respiratory Medicine. CASP checklist How good was the paper?
Reference: Borgundvaag et al. This is based, in large part, on indirect evidence illustrating the benefits of adjunctive phenobarbital including, but not limited to, reduction on the need for intubation, decreased hospital length of stay, decreased ICU admission and length of stay.
References Rosenson J, Clements C, Simon B, et al. Author information T. Several studies have indicated that dosing with phenobarbital (PO or IV) is safe and effective at decreasing the need for escalating doses of benzodiazepines for EtOH withdrawal [1-6]. The Journal of Emergency Medicine. 2013;44(3):592-598.e2. 2012.07.056.
Background Information: Delirium is a common and serious condition in patients in the intensive care unit (ICU). It is estimated to affect 30-50% of patients in the ICU and haloperidol is the most frequently used agent in treatment (3). Paper: Andersen-Ranberg NC,et al; AID-ICU Trial Group. N Engl J Med.
In shocky patients, arterial lines are often used to monitor hemodynamic parameters and inform treatment decisions. Paper: Haber, EN et al. References: Haber, EN et al. PMID: 38215002 Kaufmann T et al. which was not statistically significant [2]. Accuracy of Noninvasive Blood Pressure Monitoring in Critically Ill Adults.
Available at: HERE Branch KHR et al. The CT FIRST Trial: Should We Pan-CT After ROSC?, REBEL EM Blog, June 1, 2023. Diagnostic yield, safety, and outcomes of Head-to-pelvis sudden death CT imaging in post arrest care: The CT FIRST cohort study.
EBM Update: Steroids in Severe CAP and CT in Post ROSC OHCA #1: Dequin PF, Meziani F, Quenot JP, et al; CRICS-TriGGERSep Network. Question: In adult patients admitted to the ICU with severe CAP, does hydrocortisone compared to placebo reduce 28-day all-cause mortality? Reyes LF, Garcia E, Ibáñez-Prada ED, et al. N Engl J Med.
Secondary Outcomes: Delayed hypotension, increased ICU stay, and other relevant outcomes. It’s not mentioned whether the authors attempted to identify additional studies by checking the references of the selected articles or by contacting the original paper authors for more information. 2.89, p = 0.01.
Background Information: Acute kidney injury (AKI) is one of the most frequent complications of cardiac surgery and the cause is complex. Renal hypoperfusion from decreased glomerular filtration rate after cardiopulmonary bypass is a major contributor. Paper: Landoni G. The PROTECTION trial.
Background Information: Acute Hypotension is associated with increased morbidity and mortality. Paper: Singer S, et al. The retrospective design of this study omitted assessment of ventricular dysrhythmias related to push dose pressor administration, as they were reliant on information in the EMR. References: Singer S, et al.
If this EKG were handed to you to screen from triage without any clinical information, what would you think? The patient was upgraded to the ICU for closer monitoring. In fact, Kosuge et al. Stein et al. This is a paper worth reading : Marchik et al. Kosuge et al. Witting et al. What do you think?
Zeymer HT et al. We don’t know any of this information unfortunately and all are key in patient selection The median lactate level before revascularization was 6.9mmol/L (Range 4.6 References: Zeymer HT et al. The benefits of this strategy may be outweighed by the risk of the device-related complications (i.e. Control: 53.4%
Background Information: Vasoplegic shock is defined as hypotension with normal or increased cardiac output and can commonly occur in post-cardiac surgery patients having received cardiopulmonary bypass. Paper: Hiruy A, et al. This dysregulation of vasodilation is associated with a mortality of close to 25%. J Cardiothorac Vasc Anesth.
Click here for Direct Download of the Podcast Paper: Knack SKS et al. References: Knack SKS et al. It is possible that the induction agent used could play an important role on hemodynamic effects in critically ill adults. REBEL Cast Ep120: Etomidate vs Ketamine for RSI in the ED? Range 5 to 9) Etomidate: 7.0 Range 5 to 9) Diff -0.2;
Background Information: Obtaining definitive control of the airway, when indicated, is the responsibility of the emergency medicine physician. 2 Finally the settings initiated early in a patient’s care are often carried forward unchanged into their hospital and ICU stay. Paper: Owyang CG, et al. J Crit Care. J Crit Care.
Background Information: Cardiac arrest is a devastating event that imposes considerable human and financial burdens. Paper: Eastwood G, et al. PMID: 37318140 Mckenzie N, et al Arterial carbon dioxide tension has a nonlinear association with survival after out-of-hospital cardiac arrest: A multicentre observational study.
Background information : Alcohol has potentiating effects on the inhibitory GABA neurotransmission system and inhibitory effects on the excitatory glutamate neurotransmission system. Treatment options for alcohol withdrawal include benzodiazepines such as lorazepam, diazepam, or chlordiazepoxide, gabapentin, and phenobarbital (Buell et al.).
Fujii 2022, Sevransky 2021) Contrary to the above trial, another RCT investigated patients in the ICU with sepsis and acute respiratory distress syndrome. Clinical Question: Does high-dose vitamin C improve survival and/or persistent organ dysfunction rates in septic patients in the ICU on vasopressors? Article: Lamontagne F et al.
He requires low-dose epinephrine to maintain his mean arterial pressure (MAP) in the 60s mmHg and is transported to the cardiothoracic (CT) ICU. Carsten L, et al. Monika BM, Martin D, Balthasar E, et al. Forti A, Brugnaro P, Rauch S, et al. 2018.09.018 Romlin BS, Winberg H, Janson M, et al. 2009;338:b2085.
A recent study by Gaborit et al. 16 In another study, a series of six HIV patients with confirmed PJP that were analyzed by Limonta et al. In cases where suggestive features are already present on LUS, a chest X-ray (CXR) may offer no additional diagnostic information and may expose the patient to unnecessary radiation.
It provides highly descriptive, real-time information on clot formation, clot strength, platelet function, and fibrinolysis, which is superior to traditional coagulation tests such as INR, aPTT, and platelet count. Article: Kumar M et al. The TEG group had a shorter ICU length of stay in the first admission. Hepatology.
link] Kanaan NC, Ray J, Stewart M, et al. Unified Treatment Algorithm for the management of crotalid snakebite in the United States: results of an evidence-informed consensus workshop. link] Highlights of prescribing information. Accessed May 7, 2022. link] Buchanan JT, Thurman J. Crotalidae Envenomation. In: StatPearls.
While not specifically reviewed in this post, check out the methemoglobinemia tox card for more information about one of the other known events that can occur with local anesthetic administration. Hemodynamics slowly begin to stabilize, and the patient is transferred to the ICU for further post-cardiac arrest care. BMJ Case Rep.
While MRI is more resource and time intensive, studies have shown that a 6-minute protocol can give sufficient information to dictate treatment in the right setting. References: Gaillard F, Glick Y, Tatco V, et al. 61.4.496 Navi BB, Kamel H, Shah MP, et al. link] Burns JD, Rindler RS, Carr C, et al. Arch Neurol.
You retrieve the below relevant information… Vital signs : T 40, HR 140, BP 75/40 (52) Examination : mucous membranes slightly dry, skin turgor normal, mild dependent pitting oedema Bloods: Na 146, K 5.2, doi:10.1186/s13613-018-0402-x McNab S, Duke T, South M, et al. Regenmortel N Van, Verbrugghe W, Roelant E, et al.
Paper: van Baarle FLF et al. ICU: 42.6% vs 0% ICU length-of-stay: 9 days vs 7 days In-Hospital Mortality: 28.2% ICU Mortality: 56.7% Conversely, it may be reasonable to withhold prophylactic platelets for patients in the ICU setting due to trends of lower bleeding risk noted as well as more intensive bleeding monitoring.
Although POCUS exams are learned individually, scanning condition-related anatomic areas provides EPs with critical information, improving the opportunity to rule-in a diagnosis more confidently. Alerhand et al described ten individual echocardiographic findings of RV strain that suggest PE. 10,11 Vid 1. SubX4 Asystole RV > LV.
Hopefully in a few minutes you’ll at least have a few morsels more of information to stave off all the trainees who are undoubtedly much smarter than you on the ward round. It is important to realise that a referral to ICU for refractory cardiorenal syndrome may simply be a sign that the patient is reaching end of life.
Taking a different approach than the authors of the AHRQ report, Auerbach et al used a “look back” approach to perform both qualitative and quantitative evaluations of the types and frequencies of errors occurring in hospital settings. After developing encephalopathy and hypoxemic respiratory failure, the patient was transferred to the ICU.
Nielsen N, Wetterslev J, Cronberg T et al. By the time of the study by Nielsen et al. Kirkegaard H, Soreide E, de Haas, I et al. Kirkegaard et al. De Fazio C, Skrifvars MB, Soreide E et al. Targeted temperature management at 33°C versus 36°C after cardiac arrest. New Engl J Med. 2013;369(23):2197–2206.
The team sits down for a hot debrief once the patient is stabilised and transferred to the ICU. Exposure impairs information sharing and overall team collaboration. Frich JC, Brewster AL, Cherlin EJ, Bradley EH. The junior staff member remains silent throughout the debrief and does not attend their shift the following day.
Background Information: Multiple illness severity scores have been developed for use after out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA). Unfortunately, these rely on information that is not immediately available to providers in the early hours following return of spontaneous circulation (ROSC).
Click here for Direct Download of the Podcast Paper: Russell DW et al. References: Russell DW et al. PMID: 35707974 [ Access on Read by QxMD ] Janz DR et al. to 1.13; p = 0.03). REBEL Cast Ep111: The PrePARE II Trial – Fluid Bolus Prior to Intubation? No Bolus: 18.2% Absolute difference 2.8%; 95% CI -2.2% to 7.7%; p = 0.25
Article: How-Berlemont C, Lamhaut L, Diehl J, et al. Comparator: Delayed CAG: Patients were admitted to the ICU, and CAG was performed after 48-96 hours. There is very little information on the methodology of the meta-analysis. JAMA Cardiol. Published online June 08, 2022.
Background Information: Atrial fibrillation with rapid ventricular rate (RVR) is one of the many tachydysrhythmias we encounter in the Emergency Department (ED). 2 Amiodarone is commonly known for its anti-arrhythmic properties and a commonly used agent in the Intensive Care Unit (ICU). Paper: Mason JM, et al. Am J Emerg Med.
Contacted authors of included studies for additional information when necessary Checked multiple trial registries for unpublished literature Included studies from multiple countries Included all ages Included all languages Investigators assessed quality with standardized critical appraisal instruments from the Joanna Briggs Institute (JBI).
Article: Matchett G et al; EvK Clinical Trial Collaborators. Duration of mechanical ventilation, ICU, and percentage of vasopressor use were not significantly different. There was no information on the proportion of patients experiencing cardiovascular collapse before induction of anesthesia. The answer remains uncertain.
Evaluate and treat seizures or SE after CA in the context of other available clinical information because other systemic factors may influence the occurrence of seizures or SE and the effectiveness of treatment (90%, 18/20). Digestive Management Takeaway: Start enteral feeds when the patient gets to the ICU. Start low and go slow.
JHS’ chart review project, which identified 163 patients presenting to the ED with gluteal AFT complications in a 30-month period between 2020 and 2023, provides one of the most comprehensive and informative datasets on the breadth of AFT complications as they are currently being performed. Al Jazeera. units per patient.
However, this additional information was supportive. I took part in her ICU care and she was extubated and stable to transfer to a stepdown unit after a few days. Armstrong et al attempted to study it but may have included too many 'obvious' cases - the criteria from that paper would certainly have missed this case.
He was admitted to the ICU and transferred emergently to a facility where he could undergo emergent dialysis as a part of further evaluation and management. Can YOU mentally apply this information to the initial ECG in today's case? The QRS is narrow and T waves are much less peaked. What should ECG #1A look like? 72; Issue 9; 2018.
They informed me that she had just been hospitalized 10 days ago for "some fluid around the heart" and was discharged after one day without incident. More specific information such as definitive RV diastolic collapse was not indicated or available at this time given the obvious clinical context. Prac 15(17), 2017.
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