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Tranq dope (fentanyl-xylazine combination): A new horizon in opioid withdrawal treatment

ALiEM

Clinical impact: Rather than arguing with the patient about the likelihood of this phenomenon occurring and whether this is a true allergy, the patient is informed that they do not need to immediately start treatment to receive care in the hospital. Multimodal medication options for fentanyl-xylazine withdrawal management in London et al.

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Post-Intubation Sedation and Analgesia

Core EM

The reality of ever increasing ED volumes and longer boarding times to the ICU makes it imperative for emergency physicians to learn how to manage these critical patients. It was found that patients exposed to deep sedation in the ED had an independent higher incidence of continued deep sedation on ICU day one ( Fuller, 2019 ).

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The Kids THRIVE study: high-flow apnoeic oxygenation for intubation

Don't Forget the Bubbles

Thats exactly what Shane George et al. George S, Williams T, Humphreys S, et al. Effectiveness of Nasal High-Flow Oxygen during apnoea on Hypoxaemia and Intubation Success in Paediatric Emergency and ICU Settings: a randomised, controlled, open-label trial. Lancet Respiratory Medicine. CASP checklist How good was the paper?

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SGEM#440: I’m Gonna Need Someone To Help Me – GRACE4 AUD and CHS Management in the ED

The Skeptics' Guide to EM

Reference: Borgundvaag et al. This is based, in large part, on indirect evidence illustrating the benefits of adjunctive phenobarbital including, but not limited to, reduction on the need for intubation, decreased hospital length of stay, decreased ICU admission and length of stay.

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Phenobarbital as First-Line Medication for Alcohol Withdrawal: Have You Switched From Benzodiazepines Yet?

ALiEM

References Rosenson J, Clements C, Simon B, et al. Author information T. Several studies have indicated that dosing with phenobarbital (PO or IV) is safe and effective at decreasing the need for escalating doses of benzodiazepines for EtOH withdrawal [1-6]. The Journal of Emergency Medicine. 2013;44(3):592-598.e2. 2012.07.056.

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AID-ICU Trial: Haloperidol for Treatment of ICU Delirium

REBEL EM

Background Information: Delirium is a common and serious condition in patients in the intensive care unit (ICU). It is estimated to affect 30-50% of patients in the ICU and haloperidol is the most frequently used agent in treatment (3). Paper: Andersen-Ranberg NC,et al; AID-ICU Trial Group. N Engl J Med.

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Non-Invasive Blood Pressure Monitoring in Critically Ill Adults?

REBEL EM

In shocky patients, arterial lines are often used to monitor hemodynamic parameters and inform treatment decisions. Paper: Haber, EN et al. References: Haber, EN et al. PMID: 38215002 Kaufmann T et al. which was not statistically significant [2]. Accuracy of Noninvasive Blood Pressure Monitoring in Critically Ill Adults.

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