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AID-ICU Trial: Haloperidol for Treatment of ICU Delirium

REBEL EM

Background Information: Delirium is a common and serious condition in patients in the intensive care unit (ICU). It is estimated to affect 30-50% of patients in the ICU and haloperidol is the most frequently used agent in treatment (3). Paper: Andersen-Ranberg NC,et al; AID-ICU Trial Group. N Engl J Med.

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Post-Intubation Sedation and Analgesia

Core EM

The reality of ever increasing ED volumes and longer boarding times to the ICU makes it imperative for emergency physicians to learn how to manage these critical patients. It was found that patients exposed to deep sedation in the ED had an independent higher incidence of continued deep sedation on ICU day one ( Fuller, 2019 ).

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Non-Invasive Blood Pressure Monitoring in Critically Ill Adults?

REBEL EM

In shocky patients, arterial lines are often used to monitor hemodynamic parameters and inform treatment decisions. Paper: Haber, EN et al. References: Haber, EN et al. PMID: 38215002 Kaufmann T et al. which was not statistically significant [2]. Accuracy of Noninvasive Blood Pressure Monitoring in Critically Ill Adults.

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emDOCs Videocast: EBM Update – Steroids in Severe CAP and CT in Post ROSC OHCA

EMDocs

EBM Update: Steroids in Severe CAP and CT in Post ROSC OHCA #1: Dequin PF, Meziani F, Quenot JP, et al; CRICS-TriGGERSep Network. Question: In adult patients admitted to the ICU with severe CAP, does hydrocortisone compared to placebo reduce 28-day all-cause mortality? Reyes LF, Garcia E, Ibáñez-Prada ED, et al. N Engl J Med.

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SGEM#440: I’m Gonna Need Someone To Help Me – GRACE4 AUD and CHS Management in the ED

The Skeptics' Guide to EM

Reference: Borgundvaag et al. This is based, in large part, on indirect evidence illustrating the benefits of adjunctive phenobarbital including, but not limited to, reduction on the need for intubation, decreased hospital length of stay, decreased ICU admission and length of stay.

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The PROTECTION Trial – A Randomized Trial of Intravenous Amino Acids for Kidney Protection

REBEL EM

Background Information: Acute kidney injury (AKI) is one of the most frequent complications of cardiac surgery and the cause is complex. Renal hypoperfusion from decreased glomerular filtration rate after cardiopulmonary bypass is a major contributor. Paper: Landoni G. The PROTECTION trial.

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REBEL Cast Ep119: A Discussion with Scott Weingart on the CT FIRST Trial

REBEL EM

Available at: HERE Branch KHR et al. The CT FIRST Trial: Should We Pan-CT After ROSC?, REBEL EM Blog, June 1, 2023. Diagnostic yield, safety, and outcomes of Head-to-pelvis sudden death CT imaging in post arrest care: The CT FIRST cohort study.

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