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Background: An update to our 2015 post on HIET for beta-adrenergic receptor and calcium channel antagonists overdose. Beta-adrenergic receptor antagonists (Beta blockers, BB) and calcium channel antagonists (calcium channel blockers) are common drugs that can produce profound cardiac depression and shock when taken in overdose.
A 20-something presented after a huge verapamil overdose in cardiogenic shock. And she does not know that this is an overdose; she thinks it is a patient with chest pain!! He was admitted to the ICU and was unstable, in shock, overnight. Verapamil overdose is complex and VERY dangerous. The initial K was 3.0
Click here for Direct Download of the Podcast Paper: Bouzat P et al. References: Bouzat P et al. PMID: 36942533 Innerhofer P et al. PMID: 28457980 Jehan F et al. PMID: 29664892 Zeeshan M et al. High-quality studies are needed to determine the utility of this intervention. to 3.33; P = 0.72 to 2.10; P = 0.03
Click here for Direct Download of the Podcast Paper: Knack SKS et al. References: Knack SKS et al. It is possible that the induction agent used could play an important role on hemodynamic effects in critically ill adults. REBEL Cast Ep120: Etomidate vs Ketamine for RSI in the ED? Range 5 to 9) Etomidate: 7.0 Range 5 to 9) Diff -0.2;
He requires low-dose epinephrine to maintain his mean arterial pressure (MAP) in the 60s mmHg and is transported to the cardiothoracic (CT) ICU. In our case, the patient had accidentally overdosed on drugs prior to being found. Carsten L, et al. Monika BM, Martin D, Balthasar E, et al. Forti A, Brugnaro P, Rauch S, et al.
Hemodynamics slowly begin to stabilize, and the patient is transferred to the ICU for further post-cardiac arrest care. Poisoning & Drug Overdose. doi:10.1136/bcr-2019-233119 Neal JM, Barrington MJ, Fettiplace MR, et al. The patient remains hemodynamically unstable, and bolus of 1.5 J Med Toxicol. 2008;4(3):184-191.
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