The Skeptics' Guide to EM

SEPTEMBER 21, 2024

Date: September 18, 2024 Reference: Dillon et al. Naloxone and Patient Outcomes in Out-of-Hospital Cardiac Arrests in California. Your partner asks if you want to administer naloxone as well. Today’s study looks at the role of naloxone in OHCA. JAMA Network Open.

Naloxone 262

Naloxone NARCAN Overdose CPR 262

Dr. Smith's ECG Blog

MAY 5, 2023

Narcan was not given at the scene. The "good" news — Treatment with naloxone will probably resolve the bradycardia. The patient was a 20-something woman who was found poorly responsive with altered mental status in her car. Numerous needles from self-injection of opioids were found in the car. There was no indication of hyperkalemia.

E-9-1-1 52

E-9-1-1 NARCAN Naloxone Overdose 52

ALiEM

JANUARY 6, 2025

Necrotizing fasciitis Case Question: Will naloxone reverse a xylazine overdose? No, xylazine is a non-narcotic drug and is not an opioid, thus, Narcan will not specifically reverse acute xylazine intoxication. References Papudesi, Bhavani Nagendra, et al. BMP : Na 126; K+ 5.9; up from 0.69) ESR : >100 CRP : 15.94

NARCAN 141

NARCAN Overdose Naloxone Emergency Department 141

ACEP Now

FEBRUARY 11, 2025

A 33-year-old male with a history of drug use presented to the emergency department (ED) for extreme agitation after receiving two doses of 2 mg naloxone by EMS for respiratory depression. Gummin DD, Mowry JB, Beuhler MC, et al. Todd DA, Kellogg JJ, Wallace ED, et al. Obeng S, Kamble SH, Reeves ME, et al. 2022;23(1):4-9.

NARCAN 89

NARCAN Naloxone Overdose Mental Health Services 89

EMDocs

JANUARY 22, 2025

In the field, he was given 4 mg intranasal (IN) naloxone and rescue breaths via bag valve mask. He is administered 2mg intravenous (IV) naloxone and shortly after develops precipitated withdrawal with altered mental status, diaphoresis, vomiting, and diarrhea. When should a naloxone infusion be considered?

Naloxone 96

Naloxone E-9-1-1 Overdose NARCAN 96