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Profound ST depression in II, III, aVF

Dr. Smith's ECG Blog

This 29 year old African American patient was found down, unconscious, not breathing and was given 2 mg of intranasal naloxone by a bystander. Peak plasma concentration of amphetamines is rapid ( within minutes ) following inhalation or injection. On arrival to the ED, the patient was diaphoretic, tachycardic. and had dilated pupils.

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Sickle Cell Disease Module

Don't Forget the Bubbles

SCD, therefore, is not only a mechanical disease but there are also many other cellular and plasma factors as well as endothelial interaction that generate chronic inflammation. Naloxone (opioid antidote) should be available in ED in case of severe respiratory depression. Macharia AW et al. Ware et al. 2014; 349–356.

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