The Skeptics' Guide to EM

SEPTEMBER 21, 2024

Date: September 18, 2024 Reference: Dillon et al. Reference: Dillon et al. Naloxone and Patient Outcomes in Out-of-Hospital Cardiac Arrests in California. JAMA Network Open. August 20, 2024 Guest Skeptic: Dr. Chris Root is an emergency medicine and emergency medicine service (EMS) physician at the University of New Mexico, Albuquerque.

Naloxone 262

Naloxone NARCAN Overdose CPR 262

EMDocs

APRIL 22, 2024

The Accu-Chek was 214, and there was no response to empiric Narcan administration. Alerhand et al described ten individual echocardiographic findings of RV strain that suggest PE. Advanced cardiac life support (ACLS) had been initiated and on arrival at the ED, the patient was found to have Pulseless Electrical Activity (PEA).

ED 98

ED NARCAN ALS OR 98

Dr. Smith's ECG Blog

MAY 5, 2023

Narcan was not given at the scene. These mathematical relationships of relative deflection size with absence of any deflection at all in lead I — are most commonly encountered when there is some type of artifact caused by movement or other interference originating from the Left Leg. QUESTION: Do YOU agree with either Dr. Meyers or myself?

E-9-1-1 52

E-9-1-1 NARCAN Naloxone Overdose 52

ALiEM

JANUARY 6, 2025

No, xylazine is a non-narcotic drug and is not an opioid, thus, Narcan will not specifically reverse acute xylazine intoxication. Thus, Narcan is reasonable to administer in the setting of a suspected overdose since the patients presentation can be due to combined use. References Papudesi, Bhavani Nagendra, et al.

NARCAN 141

NARCAN Overdose Naloxone Emergency Department 141

ACEP Now

FEBRUARY 11, 2025

In the acute setting, it is postulated that withdrawal may be brought on by the rapid reversal and displacement of opioid receptors from drugs such as naloxone (Narcan). Gummin DD, Mowry JB, Beuhler MC, et al. Todd DA, Kellogg JJ, Wallace ED, et al. Obeng S, Kamble SH, Reeves ME, et al. link] Accessed December 4, 2024.

NARCAN 89

NARCAN Naloxone Overdose Mental Health Services 89

EMDocs

JANUARY 22, 2025

DOI: [link] O’Donnell J, Tanz LJ, Miller KD, et al. Naloxone reverses the analgesic, respiratory, sedative , and miotic e ffects of opioids. 6 Image 1: Structure of naloxone. Image courtesy of Wikimedia Commons. Naloxone Dosing Strategy: Start Low, Titrate Up In opioid-dependent or unknown patients, start with a lower dose (0.04

Naloxone 96

Naloxone E-9-1-1 Overdose NARCAN 96